Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives ? their stability, complexation ability in solution or when deposited on solid anionic surface

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F15%3A00440651" target="_blank" >RIV/61389013:_____/15:00440651 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/15:10295238 RIV/00216208:11320/15:10295238

Výsledek na webu

<a href="http://dx.doi.org/10.3762/bjoc.11.20" target="_blank" >http://dx.doi.org/10.3762/bjoc.11.20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3762/bjoc.11.20" target="_blank" >10.3762/bjoc.11.20</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives ? their stability, complexation ability in solution or when deposited on solid anionic surface

Popis výsledku v původním jazyce

The thermal stability of the monosubstituted cationic cyclodextrin (CD) derivatives PEMEDA-?-CD and PEMPDA-?-CD, which differ in their substituent linker length (ethylene and propylene, respectively), was studied via 1H NMR experiments. PEMPDA-?-CD exhibited higher resistance towards the Hofmann degradation and was chosen as a more suitable host molecule for further studies. Inclusion properties of PEMPDA-?-CD in solution with a series of simple aromatic guests (salicylic acid, p-methoxyphenol and p-nitroaniline) were determined by isothermal titration calorimetry (ITC) and compared to the native ?-CD. Permanently charged cationic CD derivatives were successfully deposited on the anionic solid surface of polymeric Nafion 117 membrane via electrostaticinteractions. Deposition kinetics and coverage of the surface were determined by ELSD. Finally, the ability of the CD derivatives bound to the solid surface to encapsulate aromatic compounds from aqueous solution was measured by UV?vis sp

Název v anglickém jazyce

Properties of cationic monosubstituted tetraalkylammonium cyclodextrin derivatives ? their stability, complexation ability in solution or when deposited on solid anionic surface

Popis výsledku anglicky

The thermal stability of the monosubstituted cationic cyclodextrin (CD) derivatives PEMEDA-?-CD and PEMPDA-?-CD, which differ in their substituent linker length (ethylene and propylene, respectively), was studied via 1H NMR experiments. PEMPDA-?-CD exhibited higher resistance towards the Hofmann degradation and was chosen as a more suitable host molecule for further studies. Inclusion properties of PEMPDA-?-CD in solution with a series of simple aromatic guests (salicylic acid, p-methoxyphenol and p-nitroaniline) were determined by isothermal titration calorimetry (ITC) and compared to the native ?-CD. Permanently charged cationic CD derivatives were successfully deposited on the anionic solid surface of polymeric Nafion 117 membrane via electrostaticinteractions. Deposition kinetics and coverage of the surface were determined by ELSD. Finally, the ability of the CD derivatives bound to the solid surface to encapsulate aromatic compounds from aqueous solution was measured by UV?vis sp

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP108%2F12%2F0640" target="_blank" >GAP108/12/0640: Biokompatibilní nanodimantové sondy pro multimodální zobrazování in vivo</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Beilstein Journal of Organic Chemistry

ISSN

1860-5397

e-ISSN

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Svazek periodika

11

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

192-199

Kód UT WoS článku

000349118000001

EID výsledku v databázi Scopus

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