Tungsten (VI) based „molecular puzzle” photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F18%3A00480995" target="_blank" >RIV/61389013:_____/18:00480995 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023001:_____/18:00076527

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jcis.2017.10.056" target="_blank" >http://dx.doi.org/10.1016/j.jcis.2017.10.056</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcis.2017.10.056" target="_blank" >10.1016/j.jcis.2017.10.056</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tungsten (VI) based „molecular puzzle” photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation

Popis výsledku v původním jazyce

Multimodal probes, which can be simultaneously visualized by multiple imaging modalities, enable the cellular uptake, intracellular fate, biodistribution and elimination to be tracked in organisms. In this study, we report the synthesis of crystalline WO3 and CaWO4 doped with Eu3+ or Tb3+ nanoparticles (size range of 10–160 nm) coated with polysaccharides, and these nanoparticles constitute a versatile easy-to-construct modular toolbox for multimodal imaging. The particles adsorb significant amounts of polysaccharides from the solution, providing biocompatibility and may serve as a platform for labeling. For WO3, the sorption is reversible. However, on CaWO4, stable coating is formed. CaWO4/Tb3+ coated with chemisorbed dextrin, mannan, guar gum and sodium alginate successfully underwent endocytosis with HepG2 cells and was visualized using confocal microscopy.

Název v anglickém jazyce

Tungsten (VI) based „molecular puzzle” photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation

Popis výsledku anglicky

Multimodal probes, which can be simultaneously visualized by multiple imaging modalities, enable the cellular uptake, intracellular fate, biodistribution and elimination to be tracked in organisms. In this study, we report the synthesis of crystalline WO3 and CaWO4 doped with Eu3+ or Tb3+ nanoparticles (size range of 10–160 nm) coated with polysaccharides, and these nanoparticles constitute a versatile easy-to-construct modular toolbox for multimodal imaging. The particles adsorb significant amounts of polysaccharides from the solution, providing biocompatibility and may serve as a platform for labeling. For WO3, the sorption is reversible. However, on CaWO4, stable coating is formed. CaWO4/Tb3+ coated with chemisorbed dextrin, mannan, guar gum and sodium alginate successfully underwent endocytosis with HepG2 cells and was visualized using confocal microscopy.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Colloid and Interface Science

ISSN

0021-9797

e-ISSN

—

Svazek periodika

512

Číslo periodika v rámci svazku

15 February

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

308-317

Kód UT WoS článku

000418729500034

EID výsledku v databázi Scopus

2-s2.0-85032002167