Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00544172" target="_blank" >RIV/61389013:_____/21:00544172 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/21:10432593

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0014305721003682?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0014305721003682?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.eurpolymj.2021.110634" target="_blank" >10.1016/j.eurpolymj.2021.110634</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging

Popis výsledku v původním jazyce

Polypyrrole with bioinert surface is a prospective contrast agent for photoacoustic imaging. Dextran (Dex) was successfully tested as a steric stabilizer of the dispersion polymerization producing stable polypyrrole nanoparticles (PPy-NPs). Polymerizations were mediated with three different oxidizers: iron (III) chloride, ammonium persulfate and cerium ammonium nitrate. The use of the Dex allowed good control of particle size within the range 60–200 nm through varying concentration of the Dex and polymerization temperature, with the exception of cerium mediated polymerizations, which produced 30 nm particles independently of the reaction conditions. Stabilization effect of the Dex resulted from a reversible adsorption of the Dex on the surface of nanoparticles. Spectral analysis confirmed the complete removal of the Dex from particle surfaces during washing procedure, which indicated no grafting of the Dex to PPy-NPs mediated with a radical process initiated with decay of persulfate or single electron oxidation of the Dex by cerium ammonium nitrate. Photoacoustic measurement proved detectable signals in near infrared regions.

Název v anglickém jazyce

Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging

Popis výsledku anglicky

Polypyrrole with bioinert surface is a prospective contrast agent for photoacoustic imaging. Dextran (Dex) was successfully tested as a steric stabilizer of the dispersion polymerization producing stable polypyrrole nanoparticles (PPy-NPs). Polymerizations were mediated with three different oxidizers: iron (III) chloride, ammonium persulfate and cerium ammonium nitrate. The use of the Dex allowed good control of particle size within the range 60–200 nm through varying concentration of the Dex and polymerization temperature, with the exception of cerium mediated polymerizations, which produced 30 nm particles independently of the reaction conditions. Stabilization effect of the Dex resulted from a reversible adsorption of the Dex on the surface of nanoparticles. Spectral analysis confirmed the complete removal of the Dex from particle surfaces during washing procedure, which indicated no grafting of the Dex to PPy-NPs mediated with a radical process initiated with decay of persulfate or single electron oxidation of the Dex by cerium ammonium nitrate. Photoacoustic measurement proved detectable signals in near infrared regions.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

<a href="/cs/project/GA18-05200S" target="_blank" >GA18-05200S: Vývoj nových polymerních kontrastních látek pro fotoakustické zobrazovací metody in vivo</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Polymer Journal

ISSN

0014-3057

e-ISSN

1873-1945

Svazek periodika

157

Číslo periodika v rámci svazku

15 August

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

110634

Kód UT WoS článku

000693338800007

EID výsledku v databázi Scopus

2-s2.0-85110410249