European database of explanted UHMWPE liners from total joint replacements: correlations among polymer modifications, structure, oxidation, mechanical properties and lifetime in vivo

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F23%3A00568125" target="_blank" >RIV/61389013:_____/23:00568125 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/23:10455933 RIV/00216208:11110/23:10455933

Výsledek na webu

<a href="https://www.mdpi.com/2073-4360/15/3/568" target="_blank" >https://www.mdpi.com/2073-4360/15/3/568</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/polym15030568" target="_blank" >10.3390/polym15030568</a>

Jazyk výsledku

angličtina

Název v původním jazyce

European database of explanted UHMWPE liners from total joint replacements: correlations among polymer modifications, structure, oxidation, mechanical properties and lifetime in vivo

Popis výsledku v původním jazyce

This contribution lays the foundation for the European database of explanted UHMWPE liners from total joint replacements. Three EU countries (Czech Republic, Italy and Spain) have joined their datasets containing anonymized patient data (such as age and BMI), manufacturer data (such as information on UHMWPE crosslinking, thermal treatment and sterilization), orthopedic evaluation (such as total duration of the implant in vivo and reasons for its revision) and material characterization (such as oxidative degradation and micromechanical properties). The joined database contains more than 500 entries, exhibiting gradual growth, and it is beginning to show interesting trends, which are discussed in our contribution, including (i) strong correlations between UHMWPE oxidative degradation, degree of crystallinity and microhardness, (ii) statistically significant differences between UHMWPE liners with different types of sterilization, (iii) realistic correlations between the extent of oxidative degradation and the observed reasons for total joint replacement failures. Our final objective and task for the future is to continuously expand the database, involving researchers from other European countries, in order to create a robust tool that will contribute to the better understanding of structure–properties–performance relationships in the field of arthroplasty implants.n

Název v anglickém jazyce

European database of explanted UHMWPE liners from total joint replacements: correlations among polymer modifications, structure, oxidation, mechanical properties and lifetime in vivo

Popis výsledku anglicky

This contribution lays the foundation for the European database of explanted UHMWPE liners from total joint replacements. Three EU countries (Czech Republic, Italy and Spain) have joined their datasets containing anonymized patient data (such as age and BMI), manufacturer data (such as information on UHMWPE crosslinking, thermal treatment and sterilization), orthopedic evaluation (such as total duration of the implant in vivo and reasons for its revision) and material characterization (such as oxidative degradation and micromechanical properties). The joined database contains more than 500 entries, exhibiting gradual growth, and it is beginning to show interesting trends, which are discussed in our contribution, including (i) strong correlations between UHMWPE oxidative degradation, degree of crystallinity and microhardness, (ii) statistically significant differences between UHMWPE liners with different types of sterilization, (iii) realistic correlations between the extent of oxidative degradation and the observed reasons for total joint replacement failures. Our final objective and task for the future is to continuously expand the database, involving researchers from other European countries, in order to create a robust tool that will contribute to the better understanding of structure–properties–performance relationships in the field of arthroplasty implants.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/NU21-06-00084" target="_blank" >NU21-06-00084: Vliv typu polyetylénu UHMWPE na životnost náhrady kolenního kloubu a souvislost s designem kloubních ploch implantátu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polymers

ISSN

2073-4360

e-ISSN

2073-4360

Svazek periodika

15

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

17

Strana od-do

568

Kód UT WoS článku

000929616200001

EID výsledku v databázi Scopus

2-s2.0-85147904253