“Grafting-from” synthesis of fluorinated acrylamide polymer brushes: from controlled polymerization to outstanding antifouling properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F25%3A00617396" target="_blank" >RIV/61389013:_____/25:00617396 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/25:10497880

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0032386125001612?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0032386125001612?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.polymer.2025.128175" target="_blank" >10.1016/j.polymer.2025.128175</a>

Jazyk výsledku

angličtina

Název v původním jazyce

“Grafting-from” synthesis of fluorinated acrylamide polymer brushes: from controlled polymerization to outstanding antifouling properties

Popis výsledku v původním jazyce

We report the synthesis of an antifouling polymer brush based on N-(2-fluoroethyl)acrylamide (FEAm) via the “grafting-from” method using surface-initiated atom transfer radical polymerization. We compare its antifouling properties with those of its well-known 2-hydroxyethyl-based counterparts: poly[N-(2-hydroxyethyl)acrylamide] and poly(2-hydroxyethyl acrylate). Judicious selection of surface-anchored initiating group enables the attainment of controlled polymerization kinetics and the precise tuning of brush thickness. Optimal conditions were assessed on substrates bearing two types of initiator, namely 2-bromoisobutyrate and 2-chloropropionate. Surface characterization through X-ray photoelectron and Fourier-transform infrared spectroscopies confirmed that the targeted chemical structures of the polymers were attained without the formation of side products. In addition, pFEAm brush exhibited remarkable hydrophilicity even though it does not present the functional groups typical for hydrophilic antifouling brushes, and its resistance to fouling from undiluted blood plasma was on par with other commonly employed coatings (a reduction of 95 % with respect to bare SiO2). Considering these results and its demonstrated properties as tracer in 19F MRI diagnostics, pFEAm emerges as a compelling coating material for devices requiring antifouling properties in 19F MRI.

Název v anglickém jazyce

“Grafting-from” synthesis of fluorinated acrylamide polymer brushes: from controlled polymerization to outstanding antifouling properties

Popis výsledku anglicky

We report the synthesis of an antifouling polymer brush based on N-(2-fluoroethyl)acrylamide (FEAm) via the “grafting-from” method using surface-initiated atom transfer radical polymerization. We compare its antifouling properties with those of its well-known 2-hydroxyethyl-based counterparts: poly[N-(2-hydroxyethyl)acrylamide] and poly(2-hydroxyethyl acrylate). Judicious selection of surface-anchored initiating group enables the attainment of controlled polymerization kinetics and the precise tuning of brush thickness. Optimal conditions were assessed on substrates bearing two types of initiator, namely 2-bromoisobutyrate and 2-chloropropionate. Surface characterization through X-ray photoelectron and Fourier-transform infrared spectroscopies confirmed that the targeted chemical structures of the polymers were attained without the formation of side products. In addition, pFEAm brush exhibited remarkable hydrophilicity even though it does not present the functional groups typical for hydrophilic antifouling brushes, and its resistance to fouling from undiluted blood plasma was on par with other commonly employed coatings (a reduction of 95 % with respect to bare SiO2). Considering these results and its demonstrated properties as tracer in 19F MRI diagnostics, pFEAm emerges as a compelling coating material for devices requiring antifouling properties in 19F MRI.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Polymer

ISSN

0032-3861

e-ISSN

1873-2291

Svazek periodika

323

Číslo periodika v rámci svazku

10 April

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

128175

Kód UT WoS článku

001430961600001

EID výsledku v databázi Scopus

2-s2.0-85218089083