Tailoring of the physicochemical and biological properties of polypyrrole colloids with the help of stabilizers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F25%3A00638572" target="_blank" >RIV/61389013:_____/25:00638572 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28110/25:63595799 RIV/70883521:28610/25:63595799

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0927775725020278?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0927775725020278?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2025.138124" target="_blank" >10.1016/j.colsurfa.2025.138124</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tailoring of the physicochemical and biological properties of polypyrrole colloids with the help of stabilizers

Popis výsledku v původním jazyce

Colloidal systems based on polypyrrole (PPy) have gained significant attention in multiple research fields due to their exceptional potential in both biological applications and energy storage systems. Notably, their properties can be finely tuned by the chosen stabilizers, paving the way for groundbreaking innovations. Thus, the impact of various stabilizers (poly(N-vinylpyrrolidone) (PVP), poly(vinyl alcohol) (PVAL), gelatin, culminal and poly(ethylene oxide) (PEO) on the physicochemical and biological properties of PPy colloids was investigated. The obtained colloids exhibited spherical particles. However, their size varied from 48 to 223 nm. The PPy/PEO colloid demonstrated superior electroactivity, although it was less effective in forming thin films by spin coating. In contrast, all other colloids successfully formed uniform thin films when processed by drop casting and spin coating. The used stabilizers also controlled the cytotoxicity, PPy/PEO and PPy/PVAL expressing the lowest cytotoxicity. Additionally, all the investigated PPy films exhibited excellent cytocompatibility. Thus, this study demonstrates that the use of stabilizers allows very effective control of both biological and physicochemical properties of colloids.

Název v anglickém jazyce

Tailoring of the physicochemical and biological properties of polypyrrole colloids with the help of stabilizers

Popis výsledku anglicky

Colloidal systems based on polypyrrole (PPy) have gained significant attention in multiple research fields due to their exceptional potential in both biological applications and energy storage systems. Notably, their properties can be finely tuned by the chosen stabilizers, paving the way for groundbreaking innovations. Thus, the impact of various stabilizers (poly(N-vinylpyrrolidone) (PVP), poly(vinyl alcohol) (PVAL), gelatin, culminal and poly(ethylene oxide) (PEO) on the physicochemical and biological properties of PPy colloids was investigated. The obtained colloids exhibited spherical particles. However, their size varied from 48 to 223 nm. The PPy/PEO colloid demonstrated superior electroactivity, although it was less effective in forming thin films by spin coating. In contrast, all other colloids successfully formed uniform thin films when processed by drop casting and spin coating. The used stabilizers also controlled the cytotoxicity, PPy/PEO and PPy/PVAL expressing the lowest cytotoxicity. Additionally, all the investigated PPy films exhibited excellent cytocompatibility. Thus, this study demonstrates that the use of stabilizers allows very effective control of both biological and physicochemical properties of colloids.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Surfaces A-Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

1873-4359

Svazek periodika

727

Číslo periodika v rámci svazku

Part 1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

138124

Kód UT WoS článku

001566812700001

EID výsledku v databázi Scopus

2-s2.0-105014508751