Treatment of phenylalanine and tyrosine in phosphate-buffered saline by plasma-supplied oxygen atoms: Chemical characterization and bactericidal effects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F22%3A00567035" target="_blank" >RIV/61389021:_____/22:00567035 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200079" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/ppap.202200079</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ppap.202200079" target="_blank" >10.1002/ppap.202200079</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Treatment of phenylalanine and tyrosine in phosphate-buffered saline by plasma-supplied oxygen atoms: Chemical characterization and bactericidal effects

Popis výsledku v původním jazyce

Plasma-treated liquid media containing amino acids have been shown to be effective as disinfectants and antitumor agents. The current study presents chemical analyses and bactericidal properties of mixtures formed by the treatment of phenylalanine and tyrosine in phosphate-buffered saline in He/O2 plasma. A major process observed was the formation of amino acid mono- and di-chloramines accompanied by the oxidation of the amino acid aromatic ring. The chemical activity of treated solutions lasted up to 90 min after plasma treatment. After being acidified to ~pH 3, the treated solutions exhibited a bactericidal effect against Escherichia coli. This effect was associated with the post-discharge reactions of amino acid dichloramines and the formation of C-1 nitrile as the final product.

Název v anglickém jazyce

Treatment of phenylalanine and tyrosine in phosphate-buffered saline by plasma-supplied oxygen atoms: Chemical characterization and bactericidal effects

Popis výsledku anglicky

Plasma-treated liquid media containing amino acids have been shown to be effective as disinfectants and antitumor agents. The current study presents chemical analyses and bactericidal properties of mixtures formed by the treatment of phenylalanine and tyrosine in phosphate-buffered saline in He/O2 plasma. A major process observed was the formation of amino acid mono- and di-chloramines accompanied by the oxidation of the amino acid aromatic ring. The chemical activity of treated solutions lasted up to 90 min after plasma treatment. After being acidified to ~pH 3, the treated solutions exhibited a bactericidal effect against Escherichia coli. This effect was associated with the post-discharge reactions of amino acid dichloramines and the formation of C-1 nitrile as the final product.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

<a href="/cs/project/GA19-25026S" target="_blank" >GA19-25026S: Charakterizace chemicky reaktivních kapalin produkovaných nerovnovážným plazmatem</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Plasma Processes and Polymers

ISSN

1612-8850

e-ISSN

1612-8869

Svazek periodika

19

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

13

Strana od-do

2200079

Kód UT WoS článku

000818913300001

EID výsledku v databázi Scopus

2-s2.0-85133014451