Gene Silencing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F10%3A00375430" target="_blank" >RIV/61389030:_____/10:00375430 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-90-481-2967-6_27" target="_blank" >http://dx.doi.org/10.1007/978-90-481-2967-6_27</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-90-481-2967-6_27" target="_blank" >10.1007/978-90-481-2967-6_27</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gene Silencing

Popis výsledku v původním jazyce

By 1998, it was recognized both in animal and plant systems that rearrangements of the transgene that allowed anti-parallel RNA strands to be generated stimulated a templated degradation system (RISC complex) that includes specific small RNAs together with Argonaute proteins and Dicer-like proteins that cleave the targeted RNA into characteristic 21?25 nt degradation products. In addition to induction by anti-parallel RNAs, RNAi degradation systems can be induced by virus replication intermediates as innatural host defense mechanisms. By 2001, another kind of small RNA involved in regulation of gene expression was discovered and termed microRNA. These endogenous 21 nt small RNAs play several roles in gene regulatory networks and often target other regulatory genes. Artificial small RNAs can also be designed to inactivate target genes to generate the mutant phenotypes which are useful for crop improvement.

Název v anglickém jazyce

Gene Silencing

Popis výsledku anglicky

By 1998, it was recognized both in animal and plant systems that rearrangements of the transgene that allowed anti-parallel RNA strands to be generated stimulated a templated degradation system (RISC complex) that includes specific small RNAs together with Argonaute proteins and Dicer-like proteins that cleave the targeted RNA into characteristic 21?25 nt degradation products. In addition to induction by anti-parallel RNAs, RNAi degradation systems can be induced by virus replication intermediates as innatural host defense mechanisms. By 2001, another kind of small RNA involved in regulation of gene expression was discovered and termed microRNA. These endogenous 21 nt small RNAs play several roles in gene regulatory networks and often target other regulatory genes. Artificial small RNAs can also be designed to inactivate target genes to generate the mutant phenotypes which are useful for crop improvement.

Druh

C - Kapitola v odborné knize

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Molecular Techniques in Crop Improvement, Second Edition

ISBN

978-90-481-2966-9

Počet stran výsledku

22

Strana od-do

631-652

Počet stran knihy

772

Název nakladatele

Springer

Místo vydání

Dordrecht

Kód UT WoS kapitoly

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