Medicinal natural products-An introduction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F20%3A00603666" target="_blank" >RIV/61389030:_____/20:00603666 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/20:73604950

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0065774320300087" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0065774320300087</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/bs.armc.2020.02.008" target="_blank" >10.1016/bs.armc.2020.02.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Medicinal natural products-An introduction

Popis výsledku v původním jazyce

Historically, natural products have played a pivotal role in the discovery of several modern drugs since the discovery of morphine (a narcotic analgesic mainly used in post-operative pain management) from Papaver somniferum, the very first purified chemical from a natural source, which was developed as a modern drug. Following on from this discovery, several block-buster drugs of modern time have been discovered from natural sources, and the anticancer drugs camptothecin, doxorubicin, paclitaxel, vinblastine and vincristine, are just a few examples. One of the major contributions of natural products in modern drug discovery is in the area of development of anti-infective drugs including several antibiotics, starting from the discovery of penicillin, and antimalarial drugs quinine and artemisinin, the discovery of the latter awarded Tu Youyou with the Nobel Prize in Physiology/Medicine in 2015. Because of unique chemical diversity, natural products will continue to be one of the major sources of new drug leads for drug discovery and development covering several therapeutic areas in the years to come. This chapter introduces the book, ‘Medicinal Natural Products—A Disease Focused Approach,’ and to present an overview of various topics that have been covered in various chapters in this book.

Název v anglickém jazyce

Medicinal natural products-An introduction

Popis výsledku anglicky

Historically, natural products have played a pivotal role in the discovery of several modern drugs since the discovery of morphine (a narcotic analgesic mainly used in post-operative pain management) from Papaver somniferum, the very first purified chemical from a natural source, which was developed as a modern drug. Following on from this discovery, several block-buster drugs of modern time have been discovered from natural sources, and the anticancer drugs camptothecin, doxorubicin, paclitaxel, vinblastine and vincristine, are just a few examples. One of the major contributions of natural products in modern drug discovery is in the area of development of anti-infective drugs including several antibiotics, starting from the discovery of penicillin, and antimalarial drugs quinine and artemisinin, the discovery of the latter awarded Tu Youyou with the Nobel Prize in Physiology/Medicine in 2015. Because of unique chemical diversity, natural products will continue to be one of the major sources of new drug leads for drug discovery and development covering several therapeutic areas in the years to come. This chapter introduces the book, ‘Medicinal Natural Products—A Disease Focused Approach,’ and to present an overview of various topics that have been covered in various chapters in this book.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

MEDICINAL NATURAL PRODUCTS: A DISEASE-FOCUSED APPROACH

ISBN

978-0-12-821019-2

Počet stran výsledku

44

Strana od-do

"Roč. 55"

Počet stran knihy

530

Název nakladatele

ACADEMIC PRESS INC ELSEVIER SCIENCE

Místo vydání

SAN DIEGO

Kód UT WoS kapitoly

000611827900002