Medicinal natural products - An introduction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73604950" target="_blank" >RIV/61989592:15310/20:73604950 - isvavai.cz</a>

Výsledek na webu

<a href="https://obd.upol.cz/id_publ/333184836" target="_blank" >https://obd.upol.cz/id_publ/333184836</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/bs.armc.2020.02.008" target="_blank" >10.1016/bs.armc.2020.02.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Medicinal natural products - An introduction

Popis výsledku v původním jazyce

Historically, natural products have played a pivotal role in the discovery of several modern drugs since the discovery of morphine (a narcotic analgesic mainly used in post-operative pain management) from Papaver somniferum, the very first purified chemical from a natural source, which was developed as a modern drug. Following on from this discovery, several block-buster drugs of modern time have been discovered from natural sources, and the anticancer drugs camptothecin, doxorubicin, paclitaxel, vinblastine and vincristine, are just a few examples. One of the major contributions of natural products in modern drug discovery is in the area of development of anti-infective drugs including several antibiotics, starting from the discovery of penicillin, and antimalarial drugs quinine and artemisinin, the discovery of the latter awarded Tu Youyou with the Nobel Prize in Physiology/Medicine in 2015. Because of unique chemical diversity, natural products will continue to be one of the major sources of new drug leads for drug discovery and development covering several therapeutic areas in the years to come. This chapter introduces the book, ‘Medicinal Natural Products—A Disease Focused Approach,’ and to present an overview of various topics that have been covered in various chapters in this book

Název v anglickém jazyce

Medicinal natural products - An introduction

Popis výsledku anglicky

Historically, natural products have played a pivotal role in the discovery of several modern drugs since the discovery of morphine (a narcotic analgesic mainly used in post-operative pain management) from Papaver somniferum, the very first purified chemical from a natural source, which was developed as a modern drug. Following on from this discovery, several block-buster drugs of modern time have been discovered from natural sources, and the anticancer drugs camptothecin, doxorubicin, paclitaxel, vinblastine and vincristine, are just a few examples. One of the major contributions of natural products in modern drug discovery is in the area of development of anti-infective drugs including several antibiotics, starting from the discovery of penicillin, and antimalarial drugs quinine and artemisinin, the discovery of the latter awarded Tu Youyou with the Nobel Prize in Physiology/Medicine in 2015. Because of unique chemical diversity, natural products will continue to be one of the major sources of new drug leads for drug discovery and development covering several therapeutic areas in the years to come. This chapter introduces the book, ‘Medicinal Natural Products—A Disease Focused Approach,’ and to present an overview of various topics that have been covered in various chapters in this book

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30107 - Medicinal chemistry

Projekt

<a href="/cs/project/EF16_019%2F0000868" target="_blank" >EF16_019/0000868: Molekulární, buněčný a klinický přístup ke zdravému stárnutí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Annual Reports in Medicinal Chemistry

ISBN

978-0-12-821019-2

Počet stran výsledku

44

Strana od-do

1-44

Počet stran knihy

515

Název nakladatele

Academic Press

Místo vydání

London

Kód UT WoS kapitoly

—