Development of a treatment of pregnant women suffering from epilepsy in the region of Ostrava between the years 1991 and 2006

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA1101094" target="_blank" >RIV/61988987:17110/10:A1101094 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Development of a treatment of pregnant women suffering from epilepsy in the region of Ostrava between the years 1991 and 2006

Popis výsledku v původním jazyce

The paper discusses long-term trends in the utilization of antiepileptic drugs during pregnancy and reports an analysis of their concentations at delivery. The reguest forms for routine therapeutic drug monitoring and concentrations of antiepileptic drugs at delivery collected between the years 1991-2006 were used as the data source. Monotherapy versus polytherapy, the utilization of individual antiepileptic drugs and combinations, and concentations were monitored in a group of 235 pregnancies within three 5-year periods. Monotherapy was used in 61 % in the years 1991-1995, in 68% in the years 1996-2000, and in 75 % in the years 2001-2006. During the 1 st period, the most frequently prescribed agents were phenytoin, carbamazepine and primidone, duringthe 2 nd period, carbamazepine, phenytoin, and valproic acid, and during the 3 rd period, carbamazepine, lamotrigine, and valproic acid. Concentations were mostly under the therapeutics range with an exception ofcarbamazepine and primidon

Název v anglickém jazyce

Development of a treatment of pregnant women suffering from epilepsy in the region of Ostrava between the years 1991 and 2006

Popis výsledku anglicky

The paper discusses long-term trends in the utilization of antiepileptic drugs during pregnancy and reports an analysis of their concentations at delivery. The reguest forms for routine therapeutic drug monitoring and concentrations of antiepileptic drugs at delivery collected between the years 1991-2006 were used as the data source. Monotherapy versus polytherapy, the utilization of individual antiepileptic drugs and combinations, and concentations were monitored in a group of 235 pregnancies within three 5-year periods. Monotherapy was used in 61 % in the years 1991-1995, in 68% in the years 1996-2000, and in 75 % in the years 2001-2006. During the 1 st period, the most frequently prescribed agents were phenytoin, carbamazepine and primidone, duringthe 2 nd period, carbamazepine, phenytoin, and valproic acid, and during the 3 rd period, carbamazepine, lamotrigine, and valproic acid. Concentations were mostly under the therapeutics range with an exception ofcarbamazepine and primidon

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská farmacie

ISSN

1210-7816

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

59

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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