Quantiferon-CMV Test in Prediction of Cytomegalovirus Infection After Kidney Transplantation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F10%3AA110118H" target="_blank" >RIV/61988987:17110/10:A110118H - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/10:A12013ZO RIV/00843989:_____/10:E0103645

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Quantiferon-CMV Test in Prediction of Cytomegalovirus Infection After Kidney Transplantation

Popis výsledku v původním jazyce

Infection with cytomegalovirus is a major cause of morbidity and mortality in immunosuppressed patients, including organ and bone marrow transplant recipients. The majority of CMV disease is caused by reactivation of alatent infection rather that by newly acquired virus. Many techniques have been currently available to aid in the diagnostics of CMV disease. In this report we performed a prospective evaluation of Quantiferon-CMV assay to determine whether the test is predictive of CMV disease. CD8+T-cellCMV-specific immunity was assessed in a longitudinal cohort of 14kidney transplant recipients. According to our data, subjects with higher cellular immune response measured with Quantiferon test had a lower risk of manifestation of CMV infection than subjects with lower responses.Despite the small number of patients and large intra- and interindividual variability of the data in the study, we observed the Quantiferon-CMV assay to be a sensitive specific test to detect a virus-specific T

Název v anglickém jazyce

Quantiferon-CMV Test in Prediction of Cytomegalovirus Infection After Kidney Transplantation

Popis výsledku anglicky

Infection with cytomegalovirus is a major cause of morbidity and mortality in immunosuppressed patients, including organ and bone marrow transplant recipients. The majority of CMV disease is caused by reactivation of alatent infection rather that by newly acquired virus. Many techniques have been currently available to aid in the diagnostics of CMV disease. In this report we performed a prospective evaluation of Quantiferon-CMV assay to determine whether the test is predictive of CMV disease. CD8+T-cellCMV-specific immunity was assessed in a longitudinal cohort of 14kidney transplant recipients. According to our data, subjects with higher cellular immune response measured with Quantiferon test had a lower risk of manifestation of CMV infection than subjects with lower responses.Despite the small number of patients and large intra- and interindividual variability of the data in the study, we observed the Quantiferon-CMV assay to be a sensitive specific test to detect a virus-specific T

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

TRANSPL P

ISSN

0041-1345

e-ISSN

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Svazek periodika

42

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

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Kód UT WoS článku

000284969800041

EID výsledku v databázi Scopus

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