Short-term outcomes of the new intragastric balloon End-Ball (R) for treatment of obesity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F16%3AA1701K5I" target="_blank" >RIV/61988987:17110/16:A1701K5I - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Short-term outcomes of the new intragastric balloon End-Ball (R) for treatment of obesity

Popis výsledku v původním jazyce

Introduction: Intragastric balloons (IGBs) have been successfully used to treat obesity for the last 18 years. Theseballoons are made of different materials and filled with either air or saline. It seems that balloons filled with salineresult in more effective weight loss, but are associated with worse tolerance after implantation. In contrast, balloonsfilled with air are associated with excellent tolerance, but result in less effective weight loss.Aim: To report the early safety and effectiveness results of the End-Ball&#174; balloon and to encourage discussions onhow to best use this new-generation IGB for endoscopic weight loss management.Material and methods: Twenty obese patients (mean age: 40.5 years; mean body mass index: 34.8 kg/m2) were includedin a 6-month study. Balloons were inflated with 300 ml of saline containing 5 ml of methylene blue and 300 cm3 of air.Results: No serious adverse events occurred during treatment. Patients experienced varying degrees of nausea,vomiting (mean: 3.7 times the first day), and abdominal pain after implantation. Six months (23?29 weeks) afterEnd-Ball&#174; balloon insertion, we observed a significant decrease in body weight (13.9 ?5.1 kg) and percent excessweight loss (37.9 ?12.9%). We also found a significant decrease in the levels of glycated hemoglobin (p &lt; 0.001),C-peptide (p &lt; 0.002), and triacylglycerols (p &lt; 0.001) and an increase in the concentration of high-density lipoproteincholesterol (p &lt; 0.025).Conclusions: The End-Ball&#174; IGB is a safe and effective treatment for morbid obesity, with positive effects on weightloss and saccharide metabolism.

Název v anglickém jazyce

Short-term outcomes of the new intragastric balloon End-Ball (R) for treatment of obesity

Popis výsledku anglicky

Introduction: Intragastric balloons (IGBs) have been successfully used to treat obesity for the last 18 years. Theseballoons are made of different materials and filled with either air or saline. It seems that balloons filled with salineresult in more effective weight loss, but are associated with worse tolerance after implantation. In contrast, balloonsfilled with air are associated with excellent tolerance, but result in less effective weight loss.Aim: To report the early safety and effectiveness results of the End-Ball&#174; balloon and to encourage discussions onhow to best use this new-generation IGB for endoscopic weight loss management.Material and methods: Twenty obese patients (mean age: 40.5 years; mean body mass index: 34.8 kg/m2) were includedin a 6-month study. Balloons were inflated with 300 ml of saline containing 5 ml of methylene blue and 300 cm3 of air.Results: No serious adverse events occurred during treatment. Patients experienced varying degrees of nausea,vomiting (mean: 3.7 times the first day), and abdominal pain after implantation. Six months (23?29 weeks) afterEnd-Ball&#174; balloon insertion, we observed a significant decrease in body weight (13.9 ?5.1 kg) and percent excessweight loss (37.9 ?12.9%). We also found a significant decrease in the levels of glycated hemoglobin (p &lt; 0.001),C-peptide (p &lt; 0.002), and triacylglycerols (p &lt; 0.001) and an increase in the concentration of high-density lipoproteincholesterol (p &lt; 0.025).Conclusions: The End-Ball&#174; IGB is a safe and effective treatment for morbid obesity, with positive effects on weightloss and saccharide metabolism.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Videosurgery and Other Miniinvasive Techniques

ISSN

1895-4588

e-ISSN

—

Svazek periodika

4

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

7

Strana od-do

229-235

Kód UT WoS článku

000393090200002

EID výsledku v databázi Scopus

—