Spontaneous improvement in both obstructive sleep apnea and cognitive impairment after stroke

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1801MPE" target="_blank" >RIV/61988987:17110/17:A1801MPE - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/17:10360824 RIV/61989100:27510/17:10237618 RIV/00843989:_____/17:E0106343

Výsledek na webu

<a href="http://ac.els-cdn.com/S1389945717300059/1-s2.0-S1389945717300059-main.pdf?_tid=c27187dc-3099-11e7-8382-00000aacb361&acdnat=1493882440_81b93eb86c36f3b8f6ae7f52e1c89370" target="_blank" >http://ac.els-cdn.com/S1389945717300059/1-s2.0-S1389945717300059-main.pdf?_tid=c27187dc-3099-11e7-8382-00000aacb361&acdnat=1493882440_81b93eb86c36f3b8f6ae7f52e1c89370</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sleep.2016.11.024" target="_blank" >10.1016/j.sleep.2016.11.024</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spontaneous improvement in both obstructive sleep apnea and cognitive impairment after stroke

Popis výsledku v původním jazyce

Background Knowledge available about the relationship between obstructive sleep apnea (OSA) and cognitive impairment after stroke is limited. The evolution of OSA and cognitive performance after stroke is not sufficiently described. Methods We prospectively enrolled and examined acute stroke patients without previously diagnosed OSA. The following information was collected: (1) demographics, (2) sleep cardio-respiratory polygraphy (PG) at 72 h, day seven, month three, and month 12 after stroke, (3) post-stroke functional disability tests at entry and at months three and 12, and (4) cognition (attention and orientation, memory, verbal fluency, language, and visual-spatial abilities) using the revised Addenbrooke's Cognitive Examination (ACE-R) at months three and 12. Results Of 68 patients completing the study, OSA was diagnosed in 42 (61.8%) patients. The mean apnea/hypopnea index (AHI) at study entry of 21.0 ± 13.7 spontaneously declined to 11.6 ± 11.2 at month 12 in the OSA group (p &lt; 0.0005). The total ACE-R score was significantly reduced at months three (p = 0.005) and 12 (p = 0.004) in the OSA group. Poorer performance on the subtests of memory at months 3 (p = 0.039) and 12 (p = 0.040) and verbal fluency at months 3 (p &lt; 0.005) and 12 (p &lt; 0.005) were observed in the OSA group compared to non-OSA group. Visual-spatial abilities in both the OSA (p = 0.001) and non-OSA (p = 0.046) groups and the total ACE-R score in the OSA (p = 0.005) and non-OSA (p = 0.002) groups improved. Conclusions A high prevalence of OSA and cognitive decline were present in patients after an acute stroke. Spontaneous improvements in both OSA and cognitive impairment were observed.

Název v anglickém jazyce

Spontaneous improvement in both obstructive sleep apnea and cognitive impairment after stroke

Popis výsledku anglicky

Background Knowledge available about the relationship between obstructive sleep apnea (OSA) and cognitive impairment after stroke is limited. The evolution of OSA and cognitive performance after stroke is not sufficiently described. Methods We prospectively enrolled and examined acute stroke patients without previously diagnosed OSA. The following information was collected: (1) demographics, (2) sleep cardio-respiratory polygraphy (PG) at 72 h, day seven, month three, and month 12 after stroke, (3) post-stroke functional disability tests at entry and at months three and 12, and (4) cognition (attention and orientation, memory, verbal fluency, language, and visual-spatial abilities) using the revised Addenbrooke's Cognitive Examination (ACE-R) at months three and 12. Results Of 68 patients completing the study, OSA was diagnosed in 42 (61.8%) patients. The mean apnea/hypopnea index (AHI) at study entry of 21.0 ± 13.7 spontaneously declined to 11.6 ± 11.2 at month 12 in the OSA group (p &lt; 0.0005). The total ACE-R score was significantly reduced at months three (p = 0.005) and 12 (p = 0.004) in the OSA group. Poorer performance on the subtests of memory at months 3 (p = 0.039) and 12 (p = 0.040) and verbal fluency at months 3 (p &lt; 0.005) and 12 (p &lt; 0.005) were observed in the OSA group compared to non-OSA group. Visual-spatial abilities in both the OSA (p = 0.001) and non-OSA (p = 0.046) groups and the total ACE-R score in the OSA (p = 0.005) and non-OSA (p = 0.002) groups improved. Conclusions A high prevalence of OSA and cognitive decline were present in patients after an acute stroke. Spontaneous improvements in both OSA and cognitive impairment were observed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

SLEEP MED

ISSN

1389-9457

e-ISSN

—

Svazek periodika

32

Číslo periodika v rámci svazku

1 April 2017

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

137-142

Kód UT WoS článku

000400211300021

EID výsledku v databázi Scopus

2-s2.0-85012077553