Changes in BMI in hospitalized patients during treatment with antipsychotics, depending on gender and other factors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F17%3AA1801SJN" target="_blank" >RIV/61988987:17110/17:A1801SJN - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00097041 RIV/62156489:43110/17:43911226 RIV/65269705:_____/17:00066968 RIV/00843989:_____/17:E0106333

Výsledek na webu

<a href="http://dx.doi.org/10.1080/13651501.2017.1291818" target="_blank" >http://dx.doi.org/10.1080/13651501.2017.1291818</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/13651501.2017.1291818" target="_blank" >10.1080/13651501.2017.1291818</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Changes in BMI in hospitalized patients during treatment with antipsychotics, depending on gender and other factors

Popis výsledku v původním jazyce

Objective: To investigate the differences in body mass index (BMI) changes between men and women during hospitalization.Methods: The retrospective study monitored demographic and clinical data of 462 schizophrenic patients hospitalized 737 times between 2006 and 2011. BMI analysis was performed on patients on antipsychotic medication hospitalized longer than four days.Results: Patients with an initial BMI &lt; 25 gained more weight than patients with a BMI &gt; 25 (3.94% vs. 0.23%, men 4.02% vs. 0.69%, women 3.79% vs. -0.52%, always p &lt; 0.001). Greater BMI gains were reported during the first hospitalization than during subsequent ones (3.94% vs. 1.66%, men 3.97% vs. 1.98%, women 3.88% vs. 1.18%, always p &lt; 0.001). The comparison between men and women showed a higher increase in BMI in men 2.36% vs. 1.54%, p = 0.022. Men also gained significantly more weight than women on polytherapy (+2.55% vs. +1.37%) and during subsequent hospitalizations (1.98% vs. 1.18%). For treatment with various atypical antipsychotics (AP), no significant differences were found in weight changes between men and women; during treatment using a combination of multi-receptor AP and metabolically neutral aripiprazole, a significant increase of BMI occurred in men, but not in women (p = 0.018).Conclusions: Men appear to be more prone to weight gain than women.

Název v anglickém jazyce

Changes in BMI in hospitalized patients during treatment with antipsychotics, depending on gender and other factors

Popis výsledku anglicky

Objective: To investigate the differences in body mass index (BMI) changes between men and women during hospitalization.Methods: The retrospective study monitored demographic and clinical data of 462 schizophrenic patients hospitalized 737 times between 2006 and 2011. BMI analysis was performed on patients on antipsychotic medication hospitalized longer than four days.Results: Patients with an initial BMI &lt; 25 gained more weight than patients with a BMI &gt; 25 (3.94% vs. 0.23%, men 4.02% vs. 0.69%, women 3.79% vs. -0.52%, always p &lt; 0.001). Greater BMI gains were reported during the first hospitalization than during subsequent ones (3.94% vs. 1.66%, men 3.97% vs. 1.98%, women 3.88% vs. 1.18%, always p &lt; 0.001). The comparison between men and women showed a higher increase in BMI in men 2.36% vs. 1.54%, p = 0.022. Men also gained significantly more weight than women on polytherapy (+2.55% vs. +1.37%) and during subsequent hospitalizations (1.98% vs. 1.18%). For treatment with various atypical antipsychotics (AP), no significant differences were found in weight changes between men and women; during treatment using a combination of multi-receptor AP and metabolically neutral aripiprazole, a significant increase of BMI occurred in men, but not in women (p = 0.018).Conclusions: Men appear to be more prone to weight gain than women.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

ISSN

1365-1501

e-ISSN

1471-1788

Svazek periodika

21

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

112-117

Kód UT WoS článku

000401526900006

EID výsledku v databázi Scopus

2-s2.0-85013747257