Therapeutic monitoring of carbamazepine and its active metabolite during the 1st postnatal month: Influence of drug interactions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA22029OY" target="_blank" >RIV/61988987:17110/21:A22029OY - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00843989:_____/21:E0108915

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0753332221001979?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0753332221001979?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biopha.2021.111412" target="_blank" >10.1016/j.biopha.2021.111412</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Therapeutic monitoring of carbamazepine and its active metabolite during the 1st postnatal month: Influence of drug interactions

Popis výsledku v původním jazyce

To receive information about carbamazepine and its active metabolite 10,11-epoxide transport into mature milk and suckling infants. Methods: In this cohort study, maternal serum, mature milk, and infant serum carbamazepine and epoxide levels were measured between the 6th and 29th postnatal day (carbamazepine in 1990 & ndash;2017, epoxide in 1997 & ndash;2017). Paired maternal serum, infant serum and milk levels were used for the assessment of ratios of this levels. The influence of combined treatment with enzyme-inducing antiepileptic drugs and valproic acid was assessed. Relationship between maternal serum, infant serum, and milk levels was also evaluated.

Název v anglickém jazyce

Therapeutic monitoring of carbamazepine and its active metabolite during the 1st postnatal month: Influence of drug interactions

Popis výsledku anglicky

To receive information about carbamazepine and its active metabolite 10,11-epoxide transport into mature milk and suckling infants. Methods: In this cohort study, maternal serum, mature milk, and infant serum carbamazepine and epoxide levels were measured between the 6th and 29th postnatal day (carbamazepine in 1990 & ndash;2017, epoxide in 1997 & ndash;2017). Paired maternal serum, infant serum and milk levels were used for the assessment of ratios of this levels. The influence of combined treatment with enzyme-inducing antiepileptic drugs and valproic acid was assessed. Relationship between maternal serum, infant serum, and milk levels was also evaluated.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedicine and Pharmacotherapy

ISSN

0753-3322

e-ISSN

—

Svazek periodika

137

Číslo periodika v rámci svazku

květen

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

6

Strana od-do

—

Kód UT WoS článku

000633048900001

EID výsledku v databázi Scopus

—