Intraoperative fluorescence angiography and risk factors of anastomotic leakage in mini-invasive low rectal resections

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F21%3AA2202DE4" target="_blank" >RIV/61988987:17110/21:A2202DE4 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27240/21:10247724

Výsledek na webu

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:000572624400007?SID=E1pRUgPdy5nfVZ29Get" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:000572624400007?SID=E1pRUgPdy5nfVZ29Get</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00464-020-07982-x" target="_blank" >10.1007/s00464-020-07982-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intraoperative fluorescence angiography and risk factors of anastomotic leakage in mini-invasive low rectal resections

Popis výsledku v původním jazyce

Background One of the prerequisites for proper healing of the anastomosis after a colorectal resection is adequate blood supply to the connected intestinal segments. It has been proposed that adequate visualization of the blood flow using indocyanine green (ICG) could lead to the reduction in the incidence of anastomotic leakage (AL). The aim of this study was to assess the effectiveness of intraoperative fluorescence angiography (FA) in decreasing the incidence of AL after minimally invasive low anterior resection (LAR) with total mesorectal excision (TME) in rectal cancer patients and to determine predictors of anastomotic leak. Methods From August 2015 to January 2019, data from 100 patients who underwent mini-invasive TME for rectal cancer using FA with indocyanine green (ICG) were prospectively collected and analyzed. They were compared with retrospectively analyzed data from a historical control group operated by one team of surgeons before the introduction of FA from November 2012 to August 2015 (100 patients). All patients from both groups were operated sequentially in one oncological center in Novy Jicin. Results The incidence of AL was significantly lower in the ICG group (19% vs. 9%,p = 0.042,chi(2)test). In fifteen patients in the ICG group (15%), the resection line was moved due to insufficient perfusion. Using Pearson's chi(2)test, diabetes (p = 0.036) and application of a transanal drain (NoCoil) (p = 0.032) were identified as other risk factors (RFs) for AL. Conclusion The use of ICG to visualize tissue perfusion in low rectal resections for cancer can lead to a reduction of AL.

Název v anglickém jazyce

Intraoperative fluorescence angiography and risk factors of anastomotic leakage in mini-invasive low rectal resections

Popis výsledku anglicky

Background One of the prerequisites for proper healing of the anastomosis after a colorectal resection is adequate blood supply to the connected intestinal segments. It has been proposed that adequate visualization of the blood flow using indocyanine green (ICG) could lead to the reduction in the incidence of anastomotic leakage (AL). The aim of this study was to assess the effectiveness of intraoperative fluorescence angiography (FA) in decreasing the incidence of AL after minimally invasive low anterior resection (LAR) with total mesorectal excision (TME) in rectal cancer patients and to determine predictors of anastomotic leak. Methods From August 2015 to January 2019, data from 100 patients who underwent mini-invasive TME for rectal cancer using FA with indocyanine green (ICG) were prospectively collected and analyzed. They were compared with retrospectively analyzed data from a historical control group operated by one team of surgeons before the introduction of FA from November 2012 to August 2015 (100 patients). All patients from both groups were operated sequentially in one oncological center in Novy Jicin. Results The incidence of AL was significantly lower in the ICG group (19% vs. 9%,p = 0.042,chi(2)test). In fifteen patients in the ICG group (15%), the resection line was moved due to insufficient perfusion. Using Pearson's chi(2)test, diabetes (p = 0.036) and application of a transanal drain (NoCoil) (p = 0.032) were identified as other risk factors (RFs) for AL. Conclusion The use of ICG to visualize tissue perfusion in low rectal resections for cancer can lead to a reduction of AL.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Surgical Endoscopy and Other Interventional Techniques

ISSN

0930-2794

e-ISSN

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Svazek periodika

35

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

5015-5023

Kód UT WoS článku

000572624400007

EID výsledku v databázi Scopus

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