Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F23%3AA2402L0J" target="_blank" >RIV/61988987:17110/23:A2402L0J - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61383082:_____/23:00001311

Výsledek na webu

<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:000969265700001" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:000969265700001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/svn-2022-002075" target="_blank" >10.1136/svn-2022-002075</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study

Popis výsledku v původním jazyce

Background and aim In-stent restenosis (ISR) belongs to an infrequent but potentially serious complication after carotid angioplasty and stenting in patients with severe carotid stenosis. Some of these patients might be contraindicated to repeat percutaneous transluminal angioplasty with or without stenting (rePTA/S). The purpose of the study is to compare the safety and effectiveness of carotid endarterectomy with stent removal (CEASR) and rePTA/S in patients with carotid ISR. Methods Consecutive patients with carotid ISR (>= 80%) were randomly allocated to the CEASR or rePTA/S group. The incidence of restenosis after intervention, stroke, transient ischaemic attack myocardial infarction and death 30 days and 1 year after intervention and restenosis 1 year after intervention between patients in CEASR and rePTA/S groups were statistically evaluated. Results A total of 31 patients were included in the study; 14 patients (9 males; mean age 66.3 +/- 6.6 years) were allocated to CEASR and 17 patients (10 males; mean age 68.8 +/- 5.6 years) to the rePTA/S group. The implanted stent in carotid restenosis was successfully removed in all patients in the CEASR group. No clinical vascular event was recorded periproceduraly, 30 days and 1 year after intervention in both groups. Only one patient in the CEASR group had asymptomatic occlusion of the intervened carotid artery within 30 days and one patient died in the rePTA/S group within 1 year after intervention. Restenosis after intervention was significantly greater in the rePTA/S group (mean 20.9%) than in the CEASR group (mean 0%, p=0.04), but all stenoses were <50%. Incidence of 1-year restenosis that was =70% did not differ between the rePTA/S and CEASR groups (4 vs 1 patient; p=0.233). Conclusion CEASR seems to be effective and save procedures for patients with carotid ISR and might be considered as a treatment option.

Název v anglickém jazyce

Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study

Popis výsledku anglicky

Background and aim In-stent restenosis (ISR) belongs to an infrequent but potentially serious complication after carotid angioplasty and stenting in patients with severe carotid stenosis. Some of these patients might be contraindicated to repeat percutaneous transluminal angioplasty with or without stenting (rePTA/S). The purpose of the study is to compare the safety and effectiveness of carotid endarterectomy with stent removal (CEASR) and rePTA/S in patients with carotid ISR. Methods Consecutive patients with carotid ISR (>= 80%) were randomly allocated to the CEASR or rePTA/S group. The incidence of restenosis after intervention, stroke, transient ischaemic attack myocardial infarction and death 30 days and 1 year after intervention and restenosis 1 year after intervention between patients in CEASR and rePTA/S groups were statistically evaluated. Results A total of 31 patients were included in the study; 14 patients (9 males; mean age 66.3 +/- 6.6 years) were allocated to CEASR and 17 patients (10 males; mean age 68.8 +/- 5.6 years) to the rePTA/S group. The implanted stent in carotid restenosis was successfully removed in all patients in the CEASR group. No clinical vascular event was recorded periproceduraly, 30 days and 1 year after intervention in both groups. Only one patient in the CEASR group had asymptomatic occlusion of the intervened carotid artery within 30 days and one patient died in the rePTA/S group within 1 year after intervention. Restenosis after intervention was significantly greater in the rePTA/S group (mean 20.9%) than in the CEASR group (mean 0%, p=0.04), but all stenoses were <50%. Incidence of 1-year restenosis that was =70% did not differ between the rePTA/S and CEASR groups (4 vs 1 patient; p=0.233). Conclusion CEASR seems to be effective and save procedures for patients with carotid ISR and might be considered as a treatment option.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

STROKE AND VASCULAR NEUROLOGY

ISSN

2059-8688

e-ISSN

2059-8696

Svazek periodika

—

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

399-404

Kód UT WoS článku

000969265700001

EID výsledku v databázi Scopus

—