GABAergic Interneurons in the Brain - Their Role and Detection by Wavelet Transform

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F25%3AA2603COB" target="_blank" >RIV/61988987:17110/25:A2603COB - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27240/25:10260468

Výsledek na webu

<a href="https://dl.acm.org/doi/10.1145/3774976.3774997" target="_blank" >https://dl.acm.org/doi/10.1145/3774976.3774997</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1145/3774976.3774997" target="_blank" >10.1145/3774976.3774997</a>

Jazyk výsledku

angličtina

Název v původním jazyce

GABAergic Interneurons in the Brain - Their Role and Detection by Wavelet Transform

Popis výsledku v původním jazyce

Gamma amino butyric acid (GABA) is the major inhibitory neurotransmitter in the human brain. Alterations in GABA level are associated with a variety of neurological and psychiatric disorders. GABA and glycine are considered typical neurotransmitters with an inhibitory postsynaptic effect. Unlike inhibitory neurones, excitatory interneurons characteristically release glutamate. Noninvasive in vivo measurement of GABA is hindered by its low concentration and the presence of overlapping resonances. Wavelet-based methods, however, enhance the identification of interneuron subtypes and their functional roles in neural circuits, providing deeper insights into brain dynamics and sensory processing. In this paper, we compare different approaches based on the detection of GABAergic interneurons and discuss their roles and functioning to determine brain processes under normal or pathophysiological conditions.

Název v anglickém jazyce

GABAergic Interneurons in the Brain - Their Role and Detection by Wavelet Transform

Popis výsledku anglicky

Gamma amino butyric acid (GABA) is the major inhibitory neurotransmitter in the human brain. Alterations in GABA level are associated with a variety of neurological and psychiatric disorders. GABA and glycine are considered typical neurotransmitters with an inhibitory postsynaptic effect. Unlike inhibitory neurones, excitatory interneurons characteristically release glutamate. Noninvasive in vivo measurement of GABA is hindered by its low concentration and the presence of overlapping resonances. Wavelet-based methods, however, enhance the identification of interneuron subtypes and their functional roles in neural circuits, providing deeper insights into brain dynamics and sensory processing. In this paper, we compare different approaches based on the detection of GABAergic interneurons and discuss their roles and functioning to determine brain processes under normal or pathophysiological conditions.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 12th International Conference on Bioinformatics Research and Applications

ISBN

979-840071580-8

ISSN

—

e-ISSN

—

Počet stran výsledku

6

Strana od-do

53-58

Název nakladatele

Association for Computing Machinery

Místo vydání

—

Místo konání akce

Praha

Datum konání akce

19. 9. 2025

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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