Manufacturing and Study of Mechanical Properties, Structure and Compatibility with Biological Objects of Plates and Wire from New Ti-25Nb-13Ta-5Zr Alloy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27360%2F20%3A10246948" target="_blank" >RIV/61989100:27360/20:10246948 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/2075-4701/10/12/1584/htm" target="_blank" >https://www.mdpi.com/2075-4701/10/12/1584/htm</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/met10121584" target="_blank" >10.3390/met10121584</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Manufacturing and Study of Mechanical Properties, Structure and Compatibility with Biological Objects of Plates and Wire from New Ti-25Nb-13Ta-5Zr Alloy

Popis výsledku v původním jazyce

A Ti-25Nb-13Ta-5Zr alloy was produced and studied in this work, and plates and wires were made from this alloy. It is shown that the Ti-25Nb-13Ta-5Zr alloy has the required mechanical properties and a beta-crystal phase. Microstructures were present on the surface of the alloy with a height of several hundred nm, located at a distance of 1.5-2 mu m from each other. Ti-25Nb-13Ta-5Zr was superior to nitinol in terms of the formation of long-living reactive protein species and the generation of reactive oxygen species. Cell cultivation on Ti-25Nb-13Ta-5Zr alloy surfaces revealed a significant mitotic index (2%) and a small number of nonviable cells (&lt;5%). The cells were actively attached and spread over the alloy. The biocompatibility of Ti-25Nb-13Ta-5Zr was verified by experiments on the implantation of the alloy in the form of plates and coiled wires. The surface morphology of the specimens after biological trials was not significantly altered. The experimental data we obtained suggest that Ti-25Nb-13Ta-5Zr is suitable for potential applications in biology and medicine.

Název v anglickém jazyce

Manufacturing and Study of Mechanical Properties, Structure and Compatibility with Biological Objects of Plates and Wire from New Ti-25Nb-13Ta-5Zr Alloy

Popis výsledku anglicky

A Ti-25Nb-13Ta-5Zr alloy was produced and studied in this work, and plates and wires were made from this alloy. It is shown that the Ti-25Nb-13Ta-5Zr alloy has the required mechanical properties and a beta-crystal phase. Microstructures were present on the surface of the alloy with a height of several hundred nm, located at a distance of 1.5-2 mu m from each other. Ti-25Nb-13Ta-5Zr was superior to nitinol in terms of the formation of long-living reactive protein species and the generation of reactive oxygen species. Cell cultivation on Ti-25Nb-13Ta-5Zr alloy surfaces revealed a significant mitotic index (2%) and a small number of nonviable cells (&lt;5%). The cells were actively attached and spread over the alloy. The biocompatibility of Ti-25Nb-13Ta-5Zr was verified by experiments on the implantation of the alloy in the form of plates and coiled wires. The surface morphology of the specimens after biological trials was not significantly altered. The experimental data we obtained suggest that Ti-25Nb-13Ta-5Zr is suitable for potential applications in biology and medicine.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20500 - Materials engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Metals

ISSN

2075-4701

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

—

Kód UT WoS článku

000602583100001

EID výsledku v databázi Scopus

2-s2.0-85096857234