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Designing a new medicine supply chain network considering production technology policy using two novel heuristic algorithms

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27510%2F21%3A10247577" target="_blank" >RIV/61989100:27510/21:10247577 - isvavai.cz</a>

  • Výsledek na webu

    <a href="https://www.rairo-ro.org/articles/ro/pdf/2021/03/ro200076.pdf" target="_blank" >https://www.rairo-ro.org/articles/ro/pdf/2021/03/ro200076.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1051/ro/2021031" target="_blank" >10.1051/ro/2021031</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Designing a new medicine supply chain network considering production technology policy using two novel heuristic algorithms

  • Popis výsledku v původním jazyce

    The role of medicines in health systems is increasing day by day. The medicine supply chain is a part of the health system that if not properly addressed, the concept of health in that community is unlikely to experience significant growth. To fill gaps and available challenging in the medicine supply chain network (MSCN), in the present paper, efforts have been made to propose a location-production-distribution-transportation-inventory holding problem for a multi-echelon multi-product multi-period bi-objective MSCN network under production technology policy. To design the network, a mixed-integer linear programming (MILP) model capable of minimizing the total costs of the network and the total time the transportation is developed. As the developed model was NP-hard, several meta-heuristic algorithms are used and two heuristic algorithms, namely, Improved Ant Colony Optimization (IACO) and Improved Harmony Search (IHS) algorithms are developed to solve the MSCN model in different problems. Then, some experiments were designed and solved by an optimization solver called GAMS (CPLEX) and the presented algorithms to validate the model and effectiveness of the presented algorithms. Comparison of the provided results by the presented algorithms and the exact solution is indicative of the high-quality efficiency and performance of the proposed algorithm to find a near-optimal solution within reasonable computational time. Hence, the results are compared with commercial solvers (GAMS) with the suggested algorithms in the small-sized problems and then the results of the proposed meta-heuristic algorithms with the heuristic methods are compared with each other in the large-sized problems. To tune and control the parameters of the proposed algorithms, the Taguchi method is utilized. To validate the proposed algorithms and the MSCN model, assessment metrics are used and a few sensitivity analyses are stated, respectively. The results demonstrate the high quality of the proposed IACO algorithm.

  • Název v anglickém jazyce

    Designing a new medicine supply chain network considering production technology policy using two novel heuristic algorithms

  • Popis výsledku anglicky

    The role of medicines in health systems is increasing day by day. The medicine supply chain is a part of the health system that if not properly addressed, the concept of health in that community is unlikely to experience significant growth. To fill gaps and available challenging in the medicine supply chain network (MSCN), in the present paper, efforts have been made to propose a location-production-distribution-transportation-inventory holding problem for a multi-echelon multi-product multi-period bi-objective MSCN network under production technology policy. To design the network, a mixed-integer linear programming (MILP) model capable of minimizing the total costs of the network and the total time the transportation is developed. As the developed model was NP-hard, several meta-heuristic algorithms are used and two heuristic algorithms, namely, Improved Ant Colony Optimization (IACO) and Improved Harmony Search (IHS) algorithms are developed to solve the MSCN model in different problems. Then, some experiments were designed and solved by an optimization solver called GAMS (CPLEX) and the presented algorithms to validate the model and effectiveness of the presented algorithms. Comparison of the provided results by the presented algorithms and the exact solution is indicative of the high-quality efficiency and performance of the proposed algorithm to find a near-optimal solution within reasonable computational time. Hence, the results are compared with commercial solvers (GAMS) with the suggested algorithms in the small-sized problems and then the results of the proposed meta-heuristic algorithms with the heuristic methods are compared with each other in the large-sized problems. To tune and control the parameters of the proposed algorithms, the Taguchi method is utilized. To validate the proposed algorithms and the MSCN model, assessment metrics are used and a few sensitivity analyses are stated, respectively. The results demonstrate the high quality of the proposed IACO algorithm.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    10103 - Statistics and probability

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2021

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    RAIRO - Operations Research

  • ISSN

    0399-0559

  • e-ISSN

  • Svazek periodika

    55

  • Číslo periodika v rámci svazku

    2

  • Stát vydavatele periodika

    FR - Francouzská republika

  • Počet stran výsledku

    28

  • Strana od-do

    1015-1042

  • Kód UT WoS článku

    000647643300004

  • EID výsledku v databázi Scopus

    2-s2.0-85105754548