Změny v kůži vyvolané ultrafialovým zářením

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F06%3A00003480" target="_blank" >RIV/61989592:15110/06:00003480 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Ultraviolet light induced alteration to the skin

Popis výsledku v původním jazyce

Solar light is the primary source of UV radiation for all living systems. UV photons can mediate damage through two different mechanisms, either by direct absorption of UV via cellular chromophores, resulting in excited states formation and subsequent chemical reaction, or by phosensitization mechanisms, where the UV light is absorbed by endogenous (or exogenous) sensitizers that are excited and their further reactions lead to formation of reactive oxygen species (ROS). These highly reactive species caninteract with cellular macromolecules such as DNA, proteins, fatty acids and saccharides causing oxidative damage. Direct and indirect injuries result in a number of harmful effects such as disrupted cell metabolism, morphological and ultrastructural changes, attack on the regulation pathways and, alterations in the differentiation, proliferation and apoptosis of skin cells. Processes like these can lead to erythema, sunburn, inflammation, immunosuppression, photoaging, gene mutation, a

Název v anglickém jazyce

Ultraviolet light induced alteration to the skin

Popis výsledku anglicky

Solar light is the primary source of UV radiation for all living systems. UV photons can mediate damage through two different mechanisms, either by direct absorption of UV via cellular chromophores, resulting in excited states formation and subsequent chemical reaction, or by phosensitization mechanisms, where the UV light is absorbed by endogenous (or exogenous) sensitizers that are excited and their further reactions lead to formation of reactive oxygen species (ROS). These highly reactive species caninteract with cellular macromolecules such as DNA, proteins, fatty acids and saccharides causing oxidative damage. Direct and indirect injuries result in a number of harmful effects such as disrupted cell metabolism, morphological and ultrastructural changes, attack on the regulation pathways and, alterations in the differentiation, proliferation and apoptosis of skin cells. Processes like these can lead to erythema, sunburn, inflammation, immunosuppression, photoaging, gene mutation, a

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers

ISSN

1213-8118

e-ISSN

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Svazek periodika

150

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

14

Strana od-do

25-38

Kód UT WoS článku

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EID výsledku v databázi Scopus

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