Lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg compared to Rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A10213009" target="_blank" >RIV/61989592:15110/12:10213009 - isvavai.cz</a>

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00181.x/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00181.x/pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1755-5922.2010.00181.x" target="_blank" >10.1111/j.1755-5922.2010.00181.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg compared to Rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy

Popis výsledku v původním jazyce

EZE/SIMVA was more effective than ROSUVA at lowering LDL-C, TC, non-HDL-C, and apoB in the overall study population and within both subgroups. Numerically, greater between-treatment reductions in LDL-C, TC, non-HDL-C, and apo B were seen in patients withT2DM versus those without T2DM. A significant interaction (P=0.015) was seen for LDL-C indicating that patients with T2DM achieved larger between-group reductions versus those without T2DM. Conclusions: Switching to EZE/SIMVA 10/20 mg versus ROSUVA 10 mg provided superior lipid reductions in patients with/without T2DM.

Název v anglickém jazyce

Lipid-altering efficacy of Ezetimibe/Simvastatin 10/20 mg compared to Rosuvastatin 10 mg in high-risk patients with and without type 2 diabetes mellitus inadequately controlled despite prior statin monotherapy

Popis výsledku anglicky

EZE/SIMVA was more effective than ROSUVA at lowering LDL-C, TC, non-HDL-C, and apoB in the overall study population and within both subgroups. Numerically, greater between-treatment reductions in LDL-C, TC, non-HDL-C, and apo B were seen in patients withT2DM versus those without T2DM. A significant interaction (P=0.015) was seen for LDL-C indicating that patients with T2DM achieved larger between-group reductions versus those without T2DM. Conclusions: Switching to EZE/SIMVA 10/20 mg versus ROSUVA 10 mg provided superior lipid reductions in patients with/without T2DM.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cardiovascular Therapeutic

ISSN

1755-5914

e-ISSN

—

Svazek periodika

30

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

61-74

Kód UT WoS článku

000301443500003

EID výsledku v databázi Scopus

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