Incidence of unlicensed and off-label prescription in children

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33147836" target="_blank" >RIV/61989592:15110/14:33147836 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/14:#0000664

Výsledek na webu

<a href="http://dx.doi.org/10.1186/1824-7288-40-12" target="_blank" >http://dx.doi.org/10.1186/1824-7288-40-12</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1824-7288-40-12" target="_blank" >10.1186/1824-7288-40-12</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Incidence of unlicensed and off-label prescription in children

Popis výsledku v původním jazyce

Many common drugs have not been licensed for use in children. This study evaluated the incidence of unlicensed and off-label prescriptions at the Department of Pediatrics during a period of six months. A total of 8,559 prescriptions for 4,282 children were processed. Off-label and unlicensed prescriptions were found in 9.01% and 1.26% of all prescriptions, respectively. Unlicensed prescriptions were significantly more common in boys (1.5%) than in girls (1.0%) (p = 0.037). There was no significant difference between off-label prescriptions in boys (9.0%) and in girls (9.1%) (p = 0.89). The prescription of unlicensed drugs was significantly more frequent in school age children (p { 0.0001). The most commonly prescribed unlicensed drugs were angiotensin-converting enzyme inhibitors; among off-label drugs, antihistamines and bronchodilators. This study shows that the incidence of unlicensed and off-label drug prescriptions in our patients is not as high as in other studies.

Název v anglickém jazyce

Incidence of unlicensed and off-label prescription in children

Popis výsledku anglicky

Many common drugs have not been licensed for use in children. This study evaluated the incidence of unlicensed and off-label prescriptions at the Department of Pediatrics during a period of six months. A total of 8,559 prescriptions for 4,282 children were processed. Off-label and unlicensed prescriptions were found in 9.01% and 1.26% of all prescriptions, respectively. Unlicensed prescriptions were significantly more common in boys (1.5%) than in girls (1.0%) (p = 0.037). There was no significant difference between off-label prescriptions in boys (9.0%) and in girls (9.1%) (p = 0.89). The prescription of unlicensed drugs was significantly more frequent in school age children (p { 0.0001). The most commonly prescribed unlicensed drugs were angiotensin-converting enzyme inhibitors; among off-label drugs, antihistamines and bronchodilators. This study shows that the incidence of unlicensed and off-label drug prescriptions in our patients is not as high as in other studies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Italian Journal of Pediatrics

ISSN

1824-7288

e-ISSN

—

Svazek periodika

40

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

6

Strana od-do

1-6

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—