The safety and efficacy of bridging full-dose IV-IA thrombolysis in acute ischemic stroke patients with MCA occlusion: A comparison with IV thrombolysis alone
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150063" target="_blank" >RIV/61989592:15110/14:33150063 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00098892:_____/14:#0000709
Výsledek na webu
<a href="http://dx.doi.org/10.5507/bp.2013.003" target="_blank" >http://dx.doi.org/10.5507/bp.2013.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2013.003" target="_blank" >10.5507/bp.2013.003</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The safety and efficacy of bridging full-dose IV-IA thrombolysis in acute ischemic stroke patients with MCA occlusion: A comparison with IV thrombolysis alone
Popis výsledku v původním jazyce
Aims. Early recanalization of the occluded cerebral artery is substantial for clinical improvement in acute ischemic stroke (IS) patients. The rate of achieved recanalizations using IVT is low. The aim of this study was to compare the safety and efficacyof bridging full-dose intravenous-intraarterial (IV-IA) thrombolysis to IVT alone in acute IS patients with occluded MCA. Methods. Seventy-nine consecutive IS patients with MCA occlusion were treated either with IVT alone (historic controls, Group 1) orwith full-dose IV-IA thrombolysis (Group 2). Stroke severity was evaluated using NIHSS, achieved recanalizations using transcranial Doppler (Group 1) or angiography (Group 2). Occurrence of ICH including SICH was evaluated after 24 hours. 90-day clinical outcome was evaluated using modified Rankin Scale (mRS). Results. Group 1 consisted of 50 patients (24 males, mean age 70.8 +- 10.2 years) and Group 2 of 29 patients (14 males, mean age 67.8 +- 10.0 years). No difference was found in th
Název v anglickém jazyce
The safety and efficacy of bridging full-dose IV-IA thrombolysis in acute ischemic stroke patients with MCA occlusion: A comparison with IV thrombolysis alone
Popis výsledku anglicky
Aims. Early recanalization of the occluded cerebral artery is substantial for clinical improvement in acute ischemic stroke (IS) patients. The rate of achieved recanalizations using IVT is low. The aim of this study was to compare the safety and efficacyof bridging full-dose intravenous-intraarterial (IV-IA) thrombolysis to IVT alone in acute IS patients with occluded MCA. Methods. Seventy-nine consecutive IS patients with MCA occlusion were treated either with IVT alone (historic controls, Group 1) orwith full-dose IV-IA thrombolysis (Group 2). Stroke severity was evaluated using NIHSS, achieved recanalizations using transcranial Doppler (Group 1) or angiography (Group 2). Occurrence of ICH including SICH was evaluated after 24 hours. 90-day clinical outcome was evaluated using modified Rankin Scale (mRS). Results. Group 1 consisted of 50 patients (24 males, mean age 70.8 +- 10.2 years) and Group 2 of 29 patients (14 males, mean age 67.8 +- 10.0 years). No difference was found in th
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biomedical Papers-Olomouc
ISSN
1213-8118
e-ISSN
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Svazek periodika
158
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
6
Strana od-do
391-396
Kód UT WoS článku
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EID výsledku v databázi Scopus
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