Enterobacter cloacae with a novel variant of ACT AmpC beta-lactamase originating from glaucous gull (Larus hyperboreus) in Svalbard

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33153056" target="_blank" >RIV/61989592:15110/14:33153056 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16270/14:43872946 RIV/62157124:16170/14:43872946 RIV/62157124:16810/14:43872946

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.vetmic.2014.02.015" target="_blank" >http://dx.doi.org/10.1016/j.vetmic.2014.02.015</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.vetmic.2014.02.015" target="_blank" >10.1016/j.vetmic.2014.02.015</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Enterobacter cloacae with a novel variant of ACT AmpC beta-lactamase originating from glaucous gull (Larus hyperboreus) in Svalbard

Popis výsledku v původním jazyce

We aimed at Escherichia coli and Enterobacter cloacae isolates resistant to cephalosporins and fluoroquinolones and Salmonella isolates in wild birds in Arctic Svalbard, Norway. Cloacal swabs of little auks (Alle alle, n = 215) and samples of faeces of glaucous gulls (Larus hyperboreus, n = 15) were examined. Inducible production of AmpC enzyme was detected in E. cloacae KW218 isolate. Sequence analysis of the 1146 bp PCR product of the ampC gene from this isolate revealed 99% sequence homology with thebla(ACT-14) and bla(ACT-5) AmpC beta-lactamase genes. Four, respectively six of the identified single nucleotide polymorphisms generated amino acid substitutions in the amino acid chain. As the ampC sequence polymorphism in the investigated E. cloacae strain was identified as unique, we revealed a novel variant of the ampC beta-lactamase gene bla(ACT-23). (C) 2014 Elsevier B.V. All rights reserved.

Název v anglickém jazyce

Enterobacter cloacae with a novel variant of ACT AmpC beta-lactamase originating from glaucous gull (Larus hyperboreus) in Svalbard

Popis výsledku anglicky

We aimed at Escherichia coli and Enterobacter cloacae isolates resistant to cephalosporins and fluoroquinolones and Salmonella isolates in wild birds in Arctic Svalbard, Norway. Cloacal swabs of little auks (Alle alle, n = 215) and samples of faeces of glaucous gulls (Larus hyperboreus, n = 15) were examined. Inducible production of AmpC enzyme was detected in E. cloacae KW218 isolate. Sequence analysis of the 1146 bp PCR product of the ampC gene from this isolate revealed 99% sequence homology with thebla(ACT-14) and bla(ACT-5) AmpC beta-lactamase genes. Four, respectively six of the identified single nucleotide polymorphisms generated amino acid substitutions in the amino acid chain. As the ampC sequence polymorphism in the investigated E. cloacae strain was identified as unique, we revealed a novel variant of the ampC beta-lactamase gene bla(ACT-23). (C) 2014 Elsevier B.V. All rights reserved.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

VETERINARY MICROBIOLOGY

ISSN

0378-1135

e-ISSN

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Svazek periodika

171

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

432-435

Kód UT WoS článku

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EID výsledku v databázi Scopus

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