Analogs of biologically active compounds IX. Synthesis of several new uracil and pteridine 6-azaanalogs based on cyclization of arylhydrazones derived from mesoxalic acid

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73583774" target="_blank" >RIV/61989592:15110/17:73583774 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15310/17:73583774
Výsledek na webu
<a href="http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p010.123" target="_blank" >http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p010.123</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.24820/ark.5550190.p010.123" target="_blank" >10.24820/ark.5550190.p010.123</a>

Jazyk výsledku
angličtina
Název v původním jazyce
Analogs of biologically active compounds IX. Synthesis of several new uracil and pteridine 6-azaanalogs based on cyclization of arylhydrazones derived from mesoxalic acid
Popis výsledku v původním jazyce
A series of 5C and 5N substituted 3-oxo-2-phenyl-1,2,4-triazine-6-carbonitriles and 8-imino-2-arylpyrimido[4,5-e][1,2,4]triazine-3,6(2H,5H)-diones (6-aryl-6-azapteridines) are described via a cyclocondensation reaction from the corresponding aryliminohydrazones with CDI. The required aryliminohydrazones were obtained from the starting compound – malononitrile. These prepared compounds were tested for cytotoxic activity on cancer cell lines.
Název v anglickém jazyce
Analogs of biologically active compounds IX. Synthesis of several new uracil and pteridine 6-azaanalogs based on cyclization of arylhydrazones derived from mesoxalic acid
Popis výsledku anglicky
A series of 5C and 5N substituted 3-oxo-2-phenyl-1,2,4-triazine-6-carbonitriles and 8-imino-2-arylpyrimido[4,5-e][1,2,4]triazine-3,6(2H,5H)-diones (6-aryl-6-azapteridines) are described via a cyclocondensation reaction from the corresponding aryliminohydrazones with CDI. The required aryliminohydrazones were obtained from the starting compound – malononitrile. These prepared compounds were tested for cytotoxic activity on cancer cell lines.

Projekt
<a href="/cs/project/LO1304" target="_blank" >LO1304: Podpora udržitelnosti Ústavu molekulární a translační medicíny</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění
2017
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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