Benefits of 18F-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73615875" target="_blank" >RIV/61989592:15110/21:73615875 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-4-9/benefits-of-18f-fet-pet-in-preoperative-assessment-of-glioma-heterogeneity-demonstrated-in-two-case-reports-128182" target="_blank" >https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-4-9/benefits-of-18f-fet-pet-in-preoperative-assessment-of-glioma-heterogeneity-demonstrated-in-two-case-reports-128182</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccsnn2021405" target="_blank" >10.48095/cccsnn2021405</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Benefits of 18F-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports

Popis výsledku v původním jazyce

Dear Editor, Magnetic resonance imaging is still considered the gold standard of diagnostic algorithms in gliomas. However, especially in gliomas with atypical enhancement patterns, PET could improve evaluation by monitoring processes such as cell proliferation,membrane biosynthesis, and glucose consumption [1]. Radiolabeled amino acids are frequently used PET tracers due to their high signal-to-noise ratio. In contrast to glucose derivatives, the uptake of amino acids in inflammatory cells is lower, which makes themmore specific for tumor detection [2]. Moreover, amino acids are accumulated in malignant cells owing to increased expression of type L amino acid transporters in tumor vasculature [3]. Additionally, the counter-transport system A is overexpressed in neoplastic cells and seems to correlate positively with tumor cell growth rate [4].

Název v anglickém jazyce

Benefits of 18F-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports

Popis výsledku anglicky

Dear Editor, Magnetic resonance imaging is still considered the gold standard of diagnostic algorithms in gliomas. However, especially in gliomas with atypical enhancement patterns, PET could improve evaluation by monitoring processes such as cell proliferation,membrane biosynthesis, and glucose consumption [1]. Radiolabeled amino acids are frequently used PET tracers due to their high signal-to-noise ratio. In contrast to glucose derivatives, the uptake of amino acids in inflammatory cells is lower, which makes themmore specific for tumor detection [2]. Moreover, amino acids are accumulated in malignant cells owing to increased expression of type L amino acid transporters in tumor vasculature [3]. Additionally, the counter-transport system A is overexpressed in neoplastic cells and seems to correlate positively with tumor cell growth rate [4].

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie (online)

ISSN

1802-4041

e-ISSN

—

Svazek periodika

84

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

405-409

Kód UT WoS článku

000738908000015

EID výsledku v databázi Scopus

999