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Risk of Severe COVID-19 in Non-Adherent OSA Patients

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F22%3A73614244" target="_blank" >RIV/61989592:15110/22:73614244 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/00216224:14110/22:00128092 RIV/65269705:_____/22:00076438 RIV/00098892:_____/22:10157298

  • Výsledek na webu

    <a href="https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA" target="_blank" >https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2147/PPA.S387657" target="_blank" >10.2147/PPA.S387657</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Risk of Severe COVID-19 in Non-Adherent OSA Patients

  • Popis výsledku v původním jazyce

    Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively.Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.

  • Název v anglickém jazyce

    Risk of Severe COVID-19 in Non-Adherent OSA Patients

  • Popis výsledku anglicky

    Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively.Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    30203 - Respiratory systems

Návaznosti výsledku

  • Projekt

    <a href="/cs/project/NU22-A-105" target="_blank" >NU22-A-105: Prediktivní biomarkery závažnosti a odpovědi na terapii COVID-19</a><br>

  • Návaznosti

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Ostatní

  • Rok uplatnění

    2022

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Patient Preference and Adherence

  • ISSN

    1177-889X

  • e-ISSN

  • Svazek periodika

    16

  • Číslo periodika v rámci svazku

    2022

  • Stát vydavatele periodika

    NZ - Nový Zéland

  • Počet stran výsledku

    11

  • Strana od-do

    3069-3079

  • Kód UT WoS článku

    000884754000001

  • EID výsledku v databázi Scopus

    2-s2.0-85141348758