Risk of Severe COVID-19 in Non-Adherent OSA Patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F22%3A73614244" target="_blank" >RIV/61989592:15110/22:73614244 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/22:00128092 RIV/65269705:_____/22:00076438 RIV/00098892:_____/22:10157298

Výsledek na webu

<a href="https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA" target="_blank" >https://www.dovepress.com/risk-of-severe-covid-19-in-non-adherent-osa-patients-peer-reviewed-fulltext-article-PPA</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/PPA.S387657" target="_blank" >10.2147/PPA.S387657</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Risk of Severe COVID-19 in Non-Adherent OSA Patients

Popis výsledku v původním jazyce

Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively.Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.

Název v anglickém jazyce

Risk of Severe COVID-19 in Non-Adherent OSA Patients

Popis výsledku anglicky

Background: Patients with obstructive sleep apnoea (OSA) are at increased risk of severe course of COVID-19. Vaccination remains to be the most effective prevention of complicated courses of infection. The best contemporary conservative treatment of OSA is continuous positive airway pressure (CPAP) therapy.Purpose: To compare vaccination acceptance and outcomes of COVID-19 infection between OSA patients adhering to the CPAP therapy and those who rejected CPAP and surgical therapy.Patients and Methods: Subjects were divided into two groups: group A (N = 167) were individuals with sufficient CPAP adherence (more than 4 hours per night on average) over the last 10 years. Group B (N = 106) were individuals who did not use the CPAP therapy at all and had no indications to surgical therapy.Results: Three patients in group B died, and one had a severe course of COVID-19. None of the patients in group A died or experienced a severe course of COVID-19. Group A had a significantly higher proportion of males (77.8% compared to 66% in group B) and all parameters of OSA severity. The vaccination status was similar among both groups, with a complete triple dose vaccination rate of 69.5% and 67.9% in groups A and B, respectively.Conclusion: The results show that the patients with OSA adherent to CPAP therapy were less likely to experience a severe course of COVID-19 or death than the OSA patients non-compliant with therapy, despite the former group having more severe OSA. This result underlines the importance of adherence to CPAP therapy in OSA.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30203 - Respiratory systems

Projekt

<a href="/cs/project/NU22-A-105" target="_blank" >NU22-A-105: Prediktivní biomarkery závažnosti a odpovědi na terapii COVID-19</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Patient Preference and Adherence

ISSN

1177-889X

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

2022

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

11

Strana od-do

3069-3079

Kód UT WoS článku

000884754000001

EID výsledku v databázi Scopus

2-s2.0-85141348758