Spontaneous ultra-weak photon emission imaging of oxidative metabolic processes in human skin - effect of molecular oxygen and antioxidant defense system

Kód výsledku v IS VaVaI

RIV/61989592:15310/11:33118842 - isvavai.cz

Výsledek na webu

http://dx.doi.org/10.1117/1.3616135

DOI - Digital Object Identifier

10.1117/1.3616135

Jazyk výsledku

angličtina

Název v původním jazyce

Spontaneous ultra-weak photon emission imaging of oxidative metabolic processes in human skin - effect of molecular oxygen and antioxidant defense system

Popis výsledku v původním jazyce

All living organisms emit spontaneous ultra-weak photon emission as a result of cellular metabolic processes. In this study, the involvement of reactive oxygen species (ROS) formed as the byproduct of oxidative metabolic processes in spontaneous ultra-weak photon emission was studied in the human hand skin. The effect of molecular oxygen and ROS scavengers on spontaneous ultra-weak photon emission from human skin was monitored using highly sensitive photomultiplier tube and charged couple device camera.When spontaneous ultra-weak photon emission was measured under anaerobic conditions, the photon emission was decreased, whereas under hyperaerobic condition the enhancement in photon emission was observed. Spontaneous ultra-weak photon emission measuredafter topical application of glutathione, alfa-tocopherol, ascorbate and coenzyme Q10 was observed to be decreased. These results reveal that ROS formed during the cellular metabolic processes in the epidermal cells play a significant ro

Název v anglickém jazyce

Spontaneous ultra-weak photon emission imaging of oxidative metabolic processes in human skin - effect of molecular oxygen and antioxidant defense system

Popis výsledku anglicky

All living organisms emit spontaneous ultra-weak photon emission as a result of cellular metabolic processes. In this study, the involvement of reactive oxygen species (ROS) formed as the byproduct of oxidative metabolic processes in spontaneous ultra-weak photon emission was studied in the human hand skin. The effect of molecular oxygen and ROS scavengers on spontaneous ultra-weak photon emission from human skin was monitored using highly sensitive photomultiplier tube and charged couple device camera.When spontaneous ultra-weak photon emission was measured under anaerobic conditions, the photon emission was decreased, whereas under hyperaerobic condition the enhancement in photon emission was observed. Spontaneous ultra-weak photon emission measuredafter topical application of glutathione, alfa-tocopherol, ascorbate and coenzyme Q10 was observed to be decreased. These results reveal that ROS formed during the cellular metabolic processes in the epidermal cells play a significant ro

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

ED0007/01/01: Centrum regionu Haná pro biotechnologický a zemědělský výzkum

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Z - Vyzkumny zamer (s odkazem do CEZ)
S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Biomedical Optics

ISSN

1083-3668

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

096005

Kód UT WoS článku

000296707100015

EID výsledku v databázi Scopus

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