Electrochemical oxidation of berberine and mass spectrometric identification of its oxidation products
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33142149" target="_blank" >RIV/61989592:15310/12:33142149 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15110/12:33142149
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.bioelechem.2011.09.002" target="_blank" >http://dx.doi.org/10.1016/j.bioelechem.2011.09.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bioelechem.2011.09.002" target="_blank" >10.1016/j.bioelechem.2011.09.002</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Electrochemical oxidation of berberine and mass spectrometric identification of its oxidation products
Popis výsledku v původním jazyce
Electrochemical oxidation of the isoquinoline alkaloid berberine in aqueous medium was studied by cyclic and differential pulse voltammetry at a glassy carbon electrode (GCE). Two anodic peaks of the quaternary form of berberine were observed at +1.2 V and +1.4 V (vs. SCE) in acidic and neutral solutions. When the anodic polarization exceeded the value of +1.1 V. the redox active film is formed on the GCE surface. The formation of adsorbed film was well-documented by quasireversible redox couple at +0.25 V which was studied in redox cycling experiments. In alkaline medium, a new anodic peak at +0.5 V appeared due to oxidation of berberine pseudobase to 8-oxoberberine. Solutions of berberine at different pH were subjected to controlled potential electrolysis on platinum gauze electrode and analyzed using liquid chromatography (HPLC) equipped with electrospray ionization/quadrupole time-of-flight mass spectrometry. The main water soluble monomeric product of berberine oxidation under phy
Název v anglickém jazyce
Electrochemical oxidation of berberine and mass spectrometric identification of its oxidation products
Popis výsledku anglicky
Electrochemical oxidation of the isoquinoline alkaloid berberine in aqueous medium was studied by cyclic and differential pulse voltammetry at a glassy carbon electrode (GCE). Two anodic peaks of the quaternary form of berberine were observed at +1.2 V and +1.4 V (vs. SCE) in acidic and neutral solutions. When the anodic polarization exceeded the value of +1.1 V. the redox active film is formed on the GCE surface. The formation of adsorbed film was well-documented by quasireversible redox couple at +0.25 V which was studied in redox cycling experiments. In alkaline medium, a new anodic peak at +0.5 V appeared due to oxidation of berberine pseudobase to 8-oxoberberine. Solutions of berberine at different pH were subjected to controlled potential electrolysis on platinum gauze electrode and analyzed using liquid chromatography (HPLC) equipped with electrospray ionization/quadrupole time-of-flight mass spectrometry. The main water soluble monomeric product of berberine oxidation under phy
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CG - Elektrochemie
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Bioelectrochemistry
ISSN
1567-5394
e-ISSN
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Svazek periodika
87
Číslo periodika v rámci svazku
SI
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
6
Strana od-do
15-20
Kód UT WoS článku
000309033000004
EID výsledku v databázi Scopus
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