Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33142852" target="_blank" >RIV/61989592:15310/12:33142852 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules

Popis výsledku v původním jazyce

The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.

Název v anglickém jazyce

Innovations in Biomolecular Modeling and Simulations (Vol. 2 Chap. 6): Molecular Dynamics Simulations of RNA Molecules

Popis výsledku anglicky

The central role of RNA in numerous biological processes including translation, protein localization, gene regulation, RNA processing, and viral replication calls for a detailed understanding of RNA function, structure, and conformational dynamics. Accompanying and enhancing our increasing appreciation of RNA is the rapidly expanding availability of high-resolution structures of RNAs and RNA-protein (RNP) complexes. These atomic resolution snapshots provide detailed rationalization for existing biochemical data. However, biological function depends on the dynamic evolution of structures along functional pathways. A complete understanding of the relevant structural dynamics exhibited by RNA requires monitoring timescales from picoseconds to hours through the application of a correspondingly broad range of techniques, with careful consideration given to the scope and limitation of each approach.

Druh

C - Kapitola v odborné knize

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Innovations in Biomolecular Modeling and Simulations Volume 2

ISBN

978-1-84973-462-2

Počet stran výsledku

27

Strana od-do

129-155

Počet stran knihy

350

Název nakladatele

Royal Society of Chemistry

Místo vydání

Cambridge UK

Kód UT WoS kapitoly

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