Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33141632" target="_blank" >RIV/61989592:15310/13:33141632 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/13:#0000607

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00431-013-1933-7" target="_blank" >http://dx.doi.org/10.1007/s00431-013-1933-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00431-013-1933-7" target="_blank" >10.1007/s00431-013-1933-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic

Popis výsledku v původním jazyce

Drug interactions are important potential causes of adverse drug reactions. However, studies of their occurrence in children are almost entirely lacking. This study evaluates the incidence of potential drug interactions (PDIs) in medication prescriptionsfor children. The study was performed at the University Hospital in Olomouc. PDIs in each patient's prescriptions were identified. Multivariate analysis was performed in order to assess the risk factors confounding the potential interactions. Univariateanalysis was used to assess which diagnostic groups and medication groups significantly increase or lower the odds of a potential drug?drug interaction. A total of 6,078 patients meeting the inclusion criteria entered the study. They received 19,522 prescriptions. PDIs were identified in 3.83 % of patients (moderate-to-severe cases in 0.47 %). Patient age (p=0.008), the average number of prescriptions per visit (p{0.0001), and the number of visits per year (p{0.0001) were found to incre

Název v anglickém jazyce

Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic

Popis výsledku anglicky

Drug interactions are important potential causes of adverse drug reactions. However, studies of their occurrence in children are almost entirely lacking. This study evaluates the incidence of potential drug interactions (PDIs) in medication prescriptionsfor children. The study was performed at the University Hospital in Olomouc. PDIs in each patient's prescriptions were identified. Multivariate analysis was performed in order to assess the risk factors confounding the potential interactions. Univariateanalysis was used to assess which diagnostic groups and medication groups significantly increase or lower the odds of a potential drug?drug interaction. A total of 6,078 patients meeting the inclusion criteria entered the study. They received 19,522 prescriptions. PDIs were identified in 3.83 % of patients (moderate-to-severe cases in 0.47 %). Patient age (p=0.008), the average number of prescriptions per visit (p{0.0001), and the number of visits per year (p{0.0001) were found to incre

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Pediatrics

ISSN

0340-6199

e-ISSN

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Svazek periodika

172

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

631-638

Kód UT WoS článku

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EID výsledku v databázi Scopus

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