Landscape epidemiology of neglected tick-borne pathogens in central Europe
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F21%3A73602590" target="_blank" >RIV/61989592:15310/21:73602590 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/62157124:16270/21:43879683 RIV/62157124:16810/21:43879683
Výsledek na webu
<a href="https://onlinelibrary.wiley.com/doi/10.1111/tbed.13845" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/tbed.13845</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/tbed.13845" target="_blank" >10.1111/tbed.13845</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Landscape epidemiology of neglected tick-borne pathogens in central Europe
Popis výsledku v původním jazyce
Studies of tick-borne diseases (TBDs) in Europe focus on pathogens with principal medical importance (e.g. Lyme disease and tick-borne encephalitis), but we have limited epidemiological information on the neglected pathogens, such as the members of the generaAnaplasma,Rickettsia,BabesiaandCandidatusNeoehrlichia mikurensis. Here, we integrated an extensive field sampling, laboratory analysis and GIS models to provide first publicly available information on pathogen diversity, prevalence and infection risk for four overlooked zoonotic TBDs in the Czech Republic. In addition, we assessed the effect of landscape variables on the abundance of questing ticks at different spatial scales and examined whether pathogen prevalence increased with tick density. Our data from 13,340 ticks collected in 142 municipalities showed thatA. phagocytophilum(MIR = 3.5%) andCa. Neoehrlichia mikurensis (MIR = 4.0%) pose geographically uneven risks with localized hotspots, whileRickettsia(MIR = 4.9%) andBabesia(MIR = 1.1%) had relatively homogeneous spatial distribution. Landscape variables had significant effect on tick abundance up to the scale of 1 km around the sampling sites. Questing ticks responded positively to landscape diversity and configuration, especially to forest patch density that strongly correlates with the amount of woodland-grassland ecotones. For all four pathogens, we found higher prevalence in places with higher densities of ticks, confirming the hypothesis that tick abundance amplifies the risk of TB infection. Our findings highlight the importance of landscape parameters for tick vectors, likely due to their effect on small vertebrates as reservoir hosts. Future studies should explicitly investigate the combined effect of landscape parameters and the composition and population dynamics of hosts on the host-vector-pathogen system.
Název v anglickém jazyce
Landscape epidemiology of neglected tick-borne pathogens in central Europe
Popis výsledku anglicky
Studies of tick-borne diseases (TBDs) in Europe focus on pathogens with principal medical importance (e.g. Lyme disease and tick-borne encephalitis), but we have limited epidemiological information on the neglected pathogens, such as the members of the generaAnaplasma,Rickettsia,BabesiaandCandidatusNeoehrlichia mikurensis. Here, we integrated an extensive field sampling, laboratory analysis and GIS models to provide first publicly available information on pathogen diversity, prevalence and infection risk for four overlooked zoonotic TBDs in the Czech Republic. In addition, we assessed the effect of landscape variables on the abundance of questing ticks at different spatial scales and examined whether pathogen prevalence increased with tick density. Our data from 13,340 ticks collected in 142 municipalities showed thatA. phagocytophilum(MIR = 3.5%) andCa. Neoehrlichia mikurensis (MIR = 4.0%) pose geographically uneven risks with localized hotspots, whileRickettsia(MIR = 4.9%) andBabesia(MIR = 1.1%) had relatively homogeneous spatial distribution. Landscape variables had significant effect on tick abundance up to the scale of 1 km around the sampling sites. Questing ticks responded positively to landscape diversity and configuration, especially to forest patch density that strongly correlates with the amount of woodland-grassland ecotones. For all four pathogens, we found higher prevalence in places with higher densities of ticks, confirming the hypothesis that tick abundance amplifies the risk of TB infection. Our findings highlight the importance of landscape parameters for tick vectors, likely due to their effect on small vertebrates as reservoir hosts. Future studies should explicitly investigate the combined effect of landscape parameters and the composition and population dynamics of hosts on the host-vector-pathogen system.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10618 - Ecology
Návaznosti výsledku
Projekt
<a href="/cs/project/NV16-33934A" target="_blank" >NV16-33934A: Skrytá hrozba přírodních ohnisek přehlížených, klíšťaty přenosných infekcí. Případ rodů Rickettsia, Anaplasma, Babesia</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Transboundary and Emerging Diseases
ISSN
1865-1674
e-ISSN
—
Svazek periodika
68
Číslo periodika v rámci svazku
3
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
12
Strana od-do
1685-1696
Kód UT WoS článku
000576035700001
EID výsledku v databázi Scopus
2-s2.0-85092152127