Label-free electrochemical-immunoassay of cancer biomarkers: Recent progress and challenges in the efficient diagnosis of cancer employing electroanalysis and based on point of care (POC)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F21%3A73609584" target="_blank" >RIV/61989592:15310/21:73609584 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0026265X21005087" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0026265X21005087</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.microc.2021.106424" target="_blank" >10.1016/j.microc.2021.106424</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Label-free electrochemical-immunoassay of cancer biomarkers: Recent progress and challenges in the efficient diagnosis of cancer employing electroanalysis and based on point of care (POC)

Popis výsledku v původním jazyce

The early detection of cancer is significant to have successful treatment of cancer-suffered patients. The latest progresses in molecular biology clarify that cancer biomarkers serve a crucial role in prognosis, diagnosis and affording understanding about etiology of cancer. Thus, there is a need for sensitive and easy diagnostics techniques which can determine multiplex tumor markers at low concentrations. Immunosensors have been promisingly applied in the clinical analysis field, making it qualified for accurate detection of cancer. This review is focused on cancer diagnosis through detection of cancer biomarkers by using label-free immunosensors. So, recent progress in bioanalysis of cancer biomarkers using biosensor technology was discussed. Finally, advantages and limitations of various strategies toward label-free immunosensing of cancer biomarkers were surveyed. So, various types of cancers (breast, prostate, ovarian, pancreatic and hepatocellular) can be diagnosis by labelfree immunosensor as efficient tools for point-of-care (POC) analysis.

Název v anglickém jazyce

Label-free electrochemical-immunoassay of cancer biomarkers: Recent progress and challenges in the efficient diagnosis of cancer employing electroanalysis and based on point of care (POC)

Popis výsledku anglicky

The early detection of cancer is significant to have successful treatment of cancer-suffered patients. The latest progresses in molecular biology clarify that cancer biomarkers serve a crucial role in prognosis, diagnosis and affording understanding about etiology of cancer. Thus, there is a need for sensitive and easy diagnostics techniques which can determine multiplex tumor markers at low concentrations. Immunosensors have been promisingly applied in the clinical analysis field, making it qualified for accurate detection of cancer. This review is focused on cancer diagnosis through detection of cancer biomarkers by using label-free immunosensors. So, recent progress in bioanalysis of cancer biomarkers using biosensor technology was discussed. Finally, advantages and limitations of various strategies toward label-free immunosensing of cancer biomarkers were surveyed. So, various types of cancers (breast, prostate, ovarian, pancreatic and hepatocellular) can be diagnosis by labelfree immunosensor as efficient tools for point-of-care (POC) analysis.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MICROCHEMICAL JOURNAL

ISSN

0026-265X

e-ISSN

—

Svazek periodika

168

Číslo periodika v rámci svazku

SEP

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

15

Strana od-do

"106424-1"-"106424-15"

Kód UT WoS článku

000675852600001

EID výsledku v databázi Scopus

2-s2.0-85107716624