Analysis of 3-quinuclidinol derivatives by capillary electrophoresis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15410%2F03%3A00001318" target="_blank" >RIV/61989592:15410/03:00001318 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Analysis of 3-quinuclidinol derivatives by capillary electrophoresis

Popis výsledku v původním jazyce

Capillary electrophoresis with indirect UV detection was applied to the analysis of a mixture of 3-quinuclidinol and its four quaternary derivatives (N-methyl, N-ethyl, N-propyl, and N-isopropyl derivative). 10 mM imidazole acetate buffer, pH = 4.0 offers suitable detection sensitivity (LOD = 1 mumol L-1) and permits separation of the mixture except for the pair 3-quinuclidinol- N-methyl derivative. The separation of all analytes was achieved on addition of 15 mmol L-1 beta-cyclodextrin or 25% (w/w) polyethylene glycol 2000 to the background electrolyte. The optimized method was employed for the analysis of pond water spiked with these analytes. Actual ionic mobilities of the studied compounds were measured using mobility standards (potassium, sodium,tetramethyl- and tetrabutylammonium). The migration index was derived as another identification parameter based on migration data and the precision of the obtained values is discussed in brief.

Název v anglickém jazyce

Analysis of 3-quinuclidinol derivatives by capillary electrophoresis

Popis výsledku anglicky

Capillary electrophoresis with indirect UV detection was applied to the analysis of a mixture of 3-quinuclidinol and its four quaternary derivatives (N-methyl, N-ethyl, N-propyl, and N-isopropyl derivative). 10 mM imidazole acetate buffer, pH = 4.0 offers suitable detection sensitivity (LOD = 1 mumol L-1) and permits separation of the mixture except for the pair 3-quinuclidinol- N-methyl derivative. The separation of all analytes was achieved on addition of 15 mmol L-1 beta-cyclodextrin or 25% (w/w) polyethylene glycol 2000 to the background electrolyte. The optimized method was employed for the analysis of pond water spiked with these analytes. Actual ionic mobilities of the studied compounds were measured using mobility standards (potassium, sodium,tetramethyl- and tetrabutylammonium). The migration index was derived as another identification parameter based on migration data and the precision of the obtained values is discussed in brief.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2003

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Separation Science

ISSN

1615-9306

e-ISSN

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Svazek periodika

26

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

6

Strana od-do

709-714

Kód UT WoS článku

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EID výsledku v databázi Scopus

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