Lifestyle impacts on the expression of biomarkers of DNA damage

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15510%2F12%3A33143354" target="_blank" >RIV/61989592:15510/12:33143354 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lifestyle impacts on the expression of biomarkers of DNA damage

Popis výsledku v původním jazyce

Telomeres are the chromosomal ends to preserve DNA integrity and chromosomal stability. Shortening of telomere length induces the cell damage. Human telomere length is influenced by both genetic and environmental factors and it is closely related to aging and the development of some diseases. The paper summarizes the results of the work focused on the impact of lifestyle, particularly exercise and diet, to change the length of telomeres. These works have shown that various forms of exercise and diet modify the length of telomeres. It is possible to prevent the mass aging of cells and the emergence of many diseases due to longer and more stable telomeres. Our study suggests that an appropriate exercise and a reasonable diet can be effective non-pharmacological tools to slow down the aging process. However, the evaluation of the efficacy of such approaches is extremely difficult because the measurement of effects on fitness and lifespan would require long lasting clinical studies. The de

Název v anglickém jazyce

Lifestyle impacts on the expression of biomarkers of DNA damage

Popis výsledku anglicky

Telomeres are the chromosomal ends to preserve DNA integrity and chromosomal stability. Shortening of telomere length induces the cell damage. Human telomere length is influenced by both genetic and environmental factors and it is closely related to aging and the development of some diseases. The paper summarizes the results of the work focused on the impact of lifestyle, particularly exercise and diet, to change the length of telomeres. These works have shown that various forms of exercise and diet modify the length of telomeres. It is possible to prevent the mass aging of cells and the emergence of many diseases due to longer and more stable telomeres. Our study suggests that an appropriate exercise and a reasonable diet can be effective non-pharmacological tools to slow down the aging process. However, the evaluation of the efficacy of such approaches is extremely difficult because the measurement of effects on fitness and lifespan would require long lasting clinical studies. The de

Druh

D - Stať ve sborníku

CEP obor

AK - Sport a aktivity volného času

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Sport and Physical Culture in the Mirror of the Social Sciences

ISBN

978-80-244-3134-5

ISSN

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e-ISSN

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Počet stran výsledku

7

Strana od-do

161-167

Název nakladatele

Univerzita Palackého

Místo vydání

Olomouc

Místo konání akce

Olomouc

Datum konání akce

21. 9. 2012

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000307266500021