MXenes and MXene-based materials for tissue engineering and regenerative medicine: recent advances

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F21%3A73607384" target="_blank" >RIV/61989592:15640/21:73607384 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.rsc.org/en/content/articlelanding/2021/MA/D1MA00189B" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2021/MA/D1MA00189B</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/d1ma00189b" target="_blank" >10.1039/d1ma00189b</a>

Jazyk výsledku

angličtina

Název v původním jazyce

MXenes and MXene-based materials for tissue engineering and regenerative medicine: recent advances

Popis výsledku v původním jazyce

In view of their unique planar structure and outstanding physical and chemical properties, two-dimensional (2D) materials have garnered the attention of interdisciplinary researchers in the domain of biomedical and clinical applications. MXenes are 2D transition metal carbides and nitrides with outstanding characteristics, comprising huge surface area, biocompatibility, low toxicity, significant electrical conductivity, antibacterial activity and hydrophilicity. Although numerous investigations have demonstrated the promising potential of MXenes for different biomedical applications that include biosensing, bioimaging, cancer therapy, tissue engineering, regenerative medicine, and drug delivery, there are still important challenging issues pertaining to their stability in physiological environments, sustained/controlled release of drugs, and biodegradability. The well-designed ultra-thin MXene nanosheets are deployable as promising biocompatible inorganic nanoplatforms for assorted biomedical applications via the clinical translation of nanomedicine; MXenes are good candidates for tissue engineering and regenerative medicine. Herein, recent progresses on 2D MXenes for state-of-the-art tissue engineering and regenerative medicine are discussed with emphasis on the significant challenges and future perspectives.

Název v anglickém jazyce

MXenes and MXene-based materials for tissue engineering and regenerative medicine: recent advances

Popis výsledku anglicky

In view of their unique planar structure and outstanding physical and chemical properties, two-dimensional (2D) materials have garnered the attention of interdisciplinary researchers in the domain of biomedical and clinical applications. MXenes are 2D transition metal carbides and nitrides with outstanding characteristics, comprising huge surface area, biocompatibility, low toxicity, significant electrical conductivity, antibacterial activity and hydrophilicity. Although numerous investigations have demonstrated the promising potential of MXenes for different biomedical applications that include biosensing, bioimaging, cancer therapy, tissue engineering, regenerative medicine, and drug delivery, there are still important challenging issues pertaining to their stability in physiological environments, sustained/controlled release of drugs, and biodegradability. The well-designed ultra-thin MXene nanosheets are deployable as promising biocompatible inorganic nanoplatforms for assorted biomedical applications via the clinical translation of nanomedicine; MXenes are good candidates for tissue engineering and regenerative medicine. Herein, recent progresses on 2D MXenes for state-of-the-art tissue engineering and regenerative medicine are discussed with emphasis on the significant challenges and future perspectives.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MATERIALS ADVANCES

ISSN

2633-5409

e-ISSN

—

Svazek periodika

2021

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

2906-2917

Kód UT WoS článku

000641265900001

EID výsledku v databázi Scopus

2-s2.0-85105883302