Role apoptózy neutrofilních granulocytů během experimentální infekce mléčné žlázy Streptococcus uberis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F06%3A00095107" target="_blank" >RIV/62156489:43210/06:00095107 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis

Popis výsledku v původním jazyce

The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number ofboth Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophilswere detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours afterPBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated.

Název v anglickém jazyce

The role of neutrophil apoptosis during experimentally induced Streptococcus uberis mastitis

Popis výsledku anglicky

The object of the study was to determine if apoptosis of neutrophils and their subsequent elimination from the mammary gland by macrophages are modulated by an infection of Streptococcus uberis. After PBS and S. uberis administration the total number ofboth Annexin V+/PI- neutrophils and karyopycnotic neutrophils peaked at 24 hours. The highest percentages of Annexin V+/PI- neutrophils were detected at 72 hours after PBS and S. uberis, respectively. The highest percentages of karyopycnotic neutrophilswere detected at 72 hours after PBS and 168 hours after S. uberis, respectively. The total number of MPO+ macrophages was the highest at 24 hour after PBS and 72 hours after S. uberis. The percentage of MPO+ macrophages was the highest at 72 hours afterPBS and S. uberis. The results of this study demonstrate that during experimental infection of the mammary gland by S. uberis, the apoptosis of neutrophils is modulated.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/GA524%2F03%2F1531" target="_blank" >GA524/03/1531: Role mononukleárních fagocytů během rezoluce akutního zánětu mléčné žlázy skotu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary Medicine Czech

ISSN

0375-8427

e-ISSN

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Svazek periodika

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Číslo periodika v rámci svazku

51

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

13

Strana od-do

265-277

Kód UT WoS článku

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EID výsledku v databázi Scopus

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