Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F10%3A00184606" target="_blank" >RIV/62156489:43210/10:00184606 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines
Popis výsledku v původním jazyce
Tumour markers are biochemical indicators of malignant tumour proliferation. They serve not only for diagnostics of malignant tumour diseases, but also for monitoring of effect of therapy and recurrence of disease. Serum prostate specific antigen (PSA) belongs to group of the best tumor markers, what are available to medicine at the present. In our study the Immune Enzymatic Automated Analyzer AIA 600 II was employed. Calibration curves for PSA and fPSA demonstrates very good linearity by values of R2 =0.999 in both cases. We assumed to determine levels of PSA in real samples of patients and compare to cell lines. In comparism with non-tumour cell lines we observed the enormous growth of PSA 129-times and fPSA 170-times by RVL-22 and negligible growthfor PC-3 cell lines about 2 times. Correlation of obtained data (method PSA2 and method PA) was very close with R2 =0.990.
Název v anglickém jazyce
Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines
Popis výsledku anglicky
Tumour markers are biochemical indicators of malignant tumour proliferation. They serve not only for diagnostics of malignant tumour diseases, but also for monitoring of effect of therapy and recurrence of disease. Serum prostate specific antigen (PSA) belongs to group of the best tumor markers, what are available to medicine at the present. In our study the Immune Enzymatic Automated Analyzer AIA 600 II was employed. Calibration curves for PSA and fPSA demonstrates very good linearity by values of R2 =0.999 in both cases. We assumed to determine levels of PSA in real samples of patients and compare to cell lines. In comparism with non-tumour cell lines we observed the enormous growth of PSA 129-times and fPSA 170-times by RVL-22 and negligible growthfor PC-3 cell lines about 2 times. Correlation of obtained data (method PSA2 and method PA) was very close with R2 =0.990.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CB - Analytická chemie, separace
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2010
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Biochemical Technology
ISSN
0974-2328
e-ISSN
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Svazek periodika
2
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
IN - Indická republika
Počet stran výsledku
2
Strana od-do
85-86
Kód UT WoS článku
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EID výsledku v databázi Scopus
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