Voltammetry of adiponectin and its interactions with collagen on a carbon paste electrode at femtogram level

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A00182644" target="_blank" >RIV/62156489:43210/12:00182644 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/12:PU97475

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Voltammetry of adiponectin and its interactions with collagen on a carbon paste electrode at femtogram level

Popis výsledku v původním jazyce

Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its involvement in obesity-related disorders such as insulin resistance, type 2 diabetes mellitus and atherosclerosis. Besides its well-known insulin-sensitizing, anti-inflammatory and antiatherosclerotic properties, accumulating evidence suggests that adiponectin may also have anticancer properties and be cardioprotective. The aim of this study is to investigate electrochemical behaviour of adiponectin at carbon pasteelectrode using adsorptive transfer stripping square wave voltammetry (AdTS SWV). To obtain the most sensitive analytical tool for determination of protein of interest, the time of accumulation on the surface of carbon paste electrode (CPE) and pH of supporting electrolyte (0.2 M phosphate buffer) was optimized. Under the optimized conditions (time of accumulation: 300 s, supporting electrolyte: 0.2 M phosphate buffer pH 6.98), the detection limit (3 signal/noise, S/N) for adiponectin w

Název v anglickém jazyce

Voltammetry of adiponectin and its interactions with collagen on a carbon paste electrode at femtogram level

Popis výsledku anglicky

Adiponectin, the most abundant protein secreted by white adipose tissue, is known for its involvement in obesity-related disorders such as insulin resistance, type 2 diabetes mellitus and atherosclerosis. Besides its well-known insulin-sensitizing, anti-inflammatory and antiatherosclerotic properties, accumulating evidence suggests that adiponectin may also have anticancer properties and be cardioprotective. The aim of this study is to investigate electrochemical behaviour of adiponectin at carbon pasteelectrode using adsorptive transfer stripping square wave voltammetry (AdTS SWV). To obtain the most sensitive analytical tool for determination of protein of interest, the time of accumulation on the surface of carbon paste electrode (CPE) and pH of supporting electrolyte (0.2 M phosphate buffer) was optimized. Under the optimized conditions (time of accumulation: 300 s, supporting electrolyte: 0.2 M phosphate buffer pH 6.98), the detection limit (3 signal/noise, S/N) for adiponectin w

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Electrochemical Science

ISSN

1452-3981

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

RS - Srbská republika

Počet stran výsledku

12

Strana od-do

1-12

Kód UT WoS článku

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EID výsledku v databázi Scopus

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