Multi heart-cutting two-dimensional liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry method for the determination of endocrine disrupting compounds in water

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F12%3A43908620" target="_blank" >RIV/62156489:43210/12:43908620 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.chroma.2012.02.006" target="_blank" >http://dx.doi.org/10.1016/j.chroma.2012.02.006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2012.02.006" target="_blank" >10.1016/j.chroma.2012.02.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Multi heart-cutting two-dimensional liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry method for the determination of endocrine disrupting compounds in water

Popis výsledku v původním jazyce

The multi-heart-cutting two-dimensional liquid chromatography-tandem mass spectrometry method using atmospheric pressure photoionization has been developed and successfully validated for the determination of nine endocrine disrupting compounds in river water. The method is based on the use of two different reverse-phase columns connected through a six-port two-position switching valve equipped with a 200 mu l loop. An orthogonal separation was achieved by proper selection of stationary phases, mobile phases, and the use of a gradient elution in both dimensions. The method shows excellent performance in terms of accuracy (86.2-111.1%), precision (intra-batch: 6.7-11.2%, inter-batch: 7.2-13.5%), and sensitivity (1.2-7.1 ng l(-1)). Twenty real samples collected from the Loucka and the Svratka rivers were analyzed, the studied compounds were found in all Svratka samples (9.7-11.2 ng l(-1) for beta-estradiol, 7.6-9.3 ng l(-1) for estrone, and 24.6-38.7 ng l(-1) for bisphenol A).

Název v anglickém jazyce

Multi heart-cutting two-dimensional liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry method for the determination of endocrine disrupting compounds in water

Popis výsledku anglicky

The multi-heart-cutting two-dimensional liquid chromatography-tandem mass spectrometry method using atmospheric pressure photoionization has been developed and successfully validated for the determination of nine endocrine disrupting compounds in river water. The method is based on the use of two different reverse-phase columns connected through a six-port two-position switching valve equipped with a 200 mu l loop. An orthogonal separation was achieved by proper selection of stationary phases, mobile phases, and the use of a gradient elution in both dimensions. The method shows excellent performance in terms of accuracy (86.2-111.1%), precision (intra-batch: 6.7-11.2%, inter-batch: 7.2-13.5%), and sensitivity (1.2-7.1 ng l(-1)). Twenty real samples collected from the Loucka and the Svratka rivers were analyzed, the studied compounds were found in all Svratka samples (9.7-11.2 ng l(-1) for beta-estradiol, 7.6-9.3 ng l(-1) for estrone, and 24.6-38.7 ng l(-1) for bisphenol A).

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GAP503%2F10%2F0975" target="_blank" >GAP503/10/0975: Vysoce selektivní nanostrukturované imprinty pro stanovení endokrinních disruptorů v životním prostředí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

—

Svazek periodika

1231

Číslo periodika v rámci svazku

March

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

52-58

Kód UT WoS článku

000302445000008

EID výsledku v databázi Scopus

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