The Influence of Zinc Nanocomplexes on Antioxidant Potential of the Organism

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F16%3A43910143" target="_blank" >RIV/62156489:43210/16:43910143 - isvavai.cz</a>

Výsledek na webu

<a href="https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2016/mnet_2016_full.pdf</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

The Influence of Zinc Nanocomplexes on Antioxidant Potential of the Organism

Popis výsledku v původním jazyce

The aim of our experiment was to find out if a new forms of zinc based on nanotechnology, can increase the antioxidant state in laboratory rats. The male of outbred Wistar albino rats strain were used in this experiment. The rats were sorted out to the three groups. In each of group were stabled 6 males. The first control group (Control) (n = 6) was not fed with higher doses of zinc. The second group (ZnEDT) of rats (n = 6) was fed with zinc nanoparticles chelated by ethylenediaminetetraacetic acid (EDTA) (200 mg/kg of diet). The third group (ZnNTA) of rats (n = 6) was fed with zinc nanoparticles chelated by nitrilotriacetic acid (NTA) (200 mg/kg of diet). After 15 days of zinc nanoparticles exposure, the rats were sacrificed. Immediately, the samples of blood and liver were analyzed. As markers of oxidative potential of organism were used antioxidant activity determined using FR method, level of superoxiddismutase and methallothionein and finally, content of total zinc determined by atomic absorption spectrometry (AAS). The nanozinc supplementation shows the influence on studied parameters. Our results proved the rat organism is sensitive on the used zinc nanocomplexes.

Název v anglickém jazyce

The Influence of Zinc Nanocomplexes on Antioxidant Potential of the Organism

Popis výsledku anglicky

The aim of our experiment was to find out if a new forms of zinc based on nanotechnology, can increase the antioxidant state in laboratory rats. The male of outbred Wistar albino rats strain were used in this experiment. The rats were sorted out to the three groups. In each of group were stabled 6 males. The first control group (Control) (n = 6) was not fed with higher doses of zinc. The second group (ZnEDT) of rats (n = 6) was fed with zinc nanoparticles chelated by ethylenediaminetetraacetic acid (EDTA) (200 mg/kg of diet). The third group (ZnNTA) of rats (n = 6) was fed with zinc nanoparticles chelated by nitrilotriacetic acid (NTA) (200 mg/kg of diet). After 15 days of zinc nanoparticles exposure, the rats were sacrificed. Immediately, the samples of blood and liver were analyzed. As markers of oxidative potential of organism were used antioxidant activity determined using FR method, level of superoxiddismutase and methallothionein and finally, content of total zinc determined by atomic absorption spectrometry (AAS). The nanozinc supplementation shows the influence on studied parameters. Our results proved the rat organism is sensitive on the used zinc nanocomplexes.

Druh

D - Stať ve sborníku

CEP obor

GH - Výživa hospodářských zvířat

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2016: Proceedings of International PhD Students Conference

ISBN

978-80-7509-443-8

ISSN

—

e-ISSN

—

Počet stran výsledku

1

Strana od-do

824-828

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

9. 11. 2016

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

000392968500148