Variability of Selected Genes in Relation to the Parameters of Bones in Laying Hens: A Pilot Study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F19%3A43916667" target="_blank" >RIV/62156489:43210/19:43916667 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452" target="_blank" >http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.15414/jmbfs.2019.9.special.449-452" target="_blank" >10.15414/jmbfs.2019.9.special.449-452</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Variability of Selected Genes in Relation to the Parameters of Bones in Laying Hens: A Pilot Study
Popis výsledku v původním jazyce
The aim of the present study was to screen potential key genes associated with osteoporosis in laying hens. We performed association analysis of single nucleotide polymorphisms of selected genes encoding non-collagenous proteins (IBSP, SPP1, FN1, MEPE, DCN, THBS2) with parameters of bones in a group of ISA Brown laying hens. The surveyed parameters were bone breaking strength, length, width and bone mass. In this pilot study, nineteen samples for genes encoding non-collagenous proteins were tested. The polymorphisms were detected using PCR method and sequencing. Seven polymorphisms have been discovered in genes encoding non-collagenous proteins in the genes FN1 (c.7413A>G, c.7440+57G>A, c.7440+105G>A, c.7441-71T>C), DCN (c.158C>T) and SPP1 (c.362+117G>C, c.363-88G>C), of which two of these polymorphisms were synonymous and five were in the intron. Despite the position of the found polymorphisms, no association with the mechanical parameters of the bones were found.
Název v anglickém jazyce
Variability of Selected Genes in Relation to the Parameters of Bones in Laying Hens: A Pilot Study
Popis výsledku anglicky
The aim of the present study was to screen potential key genes associated with osteoporosis in laying hens. We performed association analysis of single nucleotide polymorphisms of selected genes encoding non-collagenous proteins (IBSP, SPP1, FN1, MEPE, DCN, THBS2) with parameters of bones in a group of ISA Brown laying hens. The surveyed parameters were bone breaking strength, length, width and bone mass. In this pilot study, nineteen samples for genes encoding non-collagenous proteins were tested. The polymorphisms were detected using PCR method and sequencing. Seven polymorphisms have been discovered in genes encoding non-collagenous proteins in the genes FN1 (c.7413A>G, c.7440+57G>A, c.7440+105G>A, c.7441-71T>C), DCN (c.158C>T) and SPP1 (c.362+117G>C, c.363-88G>C), of which two of these polymorphisms were synonymous and five were in the intron. Despite the position of the found polymorphisms, no association with the mechanical parameters of the bones were found.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
40203 - Husbandry
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Microbiology, Biotechnology and Food Science
ISSN
1338-5178
e-ISSN
—
Svazek periodika
9
Číslo periodika v rámci svazku
Special Issue
Stát vydavatele periodika
SK - Slovenská republika
Počet stran výsledku
4
Strana od-do
449-452
Kód UT WoS článku
000500544500020
EID výsledku v databázi Scopus
2-s2.0-85083699043