Immunocompetence of Nyctalus noctula females during gestation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43310%2F23%3A43923254" target="_blank" >RIV/62156489:43310/23:43923254 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.ivb.cz/wp-content/uploads/Sbornik-2023-A5_FINAL.pdf" target="_blank" >https://www.ivb.cz/wp-content/uploads/Sbornik-2023-A5_FINAL.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Immunocompetence of Nyctalus noctula females during gestation

Popis výsledku v původním jazyce

Reproduction is the most energy- and nutrition-demanding period throughout the life of bat females. Daily and seasonal fluctuations of ambient temperature and insect availability strongly affect their foraging activity and reproduction success. These factors are especially pronounced in temperate bat species as offspring must grow quickly during the short warm season and accumulate resources to survive the winter. However, individual female reproduction success may influence also other factors, including parasite and pathogen load. To assess the immunocompetence of 20 female noctule bat Nyctalus noctula during pregnancy we evaluated the presence of mycobacteria in faecal samples using three different methods, i.e. direct microscopy after Ziehl-Neelsen staining, culture examination and qPCR. The majority of females was positively tested to mycobacteria presence (90%) at least once but two females were negative during all study period. The prevalence of mycobacteria shading changed during the pregnancy with the highest rate in two periods i.e. after the hibernation and shortly before the parturition. The pattern of prevalence changes differed between females with twins and singletons and it was influenced by the food freshness. At the same time, the severity of infection (copies/mL DNA of NTM) increased during the course of pregnancy but the female N. noctula were able to cope with mycobacteria.

Název v anglickém jazyce

Immunocompetence of Nyctalus noctula females during gestation

Popis výsledku anglicky

Reproduction is the most energy- and nutrition-demanding period throughout the life of bat females. Daily and seasonal fluctuations of ambient temperature and insect availability strongly affect their foraging activity and reproduction success. These factors are especially pronounced in temperate bat species as offspring must grow quickly during the short warm season and accumulate resources to survive the winter. However, individual female reproduction success may influence also other factors, including parasite and pathogen load. To assess the immunocompetence of 20 female noctule bat Nyctalus noctula during pregnancy we evaluated the presence of mycobacteria in faecal samples using three different methods, i.e. direct microscopy after Ziehl-Neelsen staining, culture examination and qPCR. The majority of females was positively tested to mycobacteria presence (90%) at least once but two females were negative during all study period. The prevalence of mycobacteria shading changed during the pregnancy with the highest rate in two periods i.e. after the hibernation and shortly before the parturition. The pattern of prevalence changes differed between females with twins and singletons and it was influenced by the food freshness. At the same time, the severity of infection (copies/mL DNA of NTM) increased during the course of pregnancy but the female N. noctula were able to cope with mycobacteria.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GA21-12719S" target="_blank" >GA21-12719S: Mykobakterie u netopýrů a jejich role ve zdraví a nemoci</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů