Prevalence of non-tuberculous mycobacteria in gestating common noctule (Nyctalus noctula) females

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F23%3A00580750" target="_blank" >RIV/68081766:_____/23:00580750 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62156489:43310/23:43924566

Výsledek na webu

<a href="https://bioone.org/journalArticle/Download?urlId=10.3161%2F15081109ACC2023.25.2.013" target="_blank" >https://bioone.org/journalArticle/Download?urlId=10.3161%2F15081109ACC2023.25.2.013</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3161/15081109ACC2023.25.2.013" target="_blank" >10.3161/15081109ACC2023.25.2.013</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence of non-tuberculous mycobacteria in gestating common noctule (Nyctalus noctula) females

Popis výsledku v původním jazyce

Especially in the temperate zone, female bats are exposed to increased energy demands during gestation. In addition, abiotic factors, such as ambient temperature and pathogen load, can significantly affect reproduction success. Bats are considered natural reservoirs for a wide variety of pathogenic agents, and have developed strong immune systems to cope. Nevertheless, very little is known about the influence of these pathogenic microorganisms on bat health as most infections are asymptomatic. In this study, we monitored presence of non-tuberculous mycobacteria (NTM) in female common noctule bats Nyctalus noctula during gestation. Eight NTM species, subspecies or complexes (Risk Group 1: Mycobacterium hiberniae and M. terrae complex. Risk Group 2: M. arupense, M. avium ssp. hominissuis, M. fortuitum, M. interjectum, M. peregrinum, M. septicum) were confirmed as part of the female gut microbiome during gestation, with representation changing during foetal development. Following hibernation, most females were infected, though infection load and severity were relatively low. Just prior to parturition, however, a high proportion of females were infected with a high, often pathogenic, NTM load. Females who gave birth to twins had a higher (though non-significant) proportion of positive samples after hibernation and before parturition. Negative correlations between two consecutive measurements suggest that female N. noctula can cope with NTM loading, even during energy-demanding pregnancies. Bat faeces appear to be a source of numerous NTM species and, as such, bats can be considered as vectors for NTM spread in the environment.

Název v anglickém jazyce

Prevalence of non-tuberculous mycobacteria in gestating common noctule (Nyctalus noctula) females

Popis výsledku anglicky

Especially in the temperate zone, female bats are exposed to increased energy demands during gestation. In addition, abiotic factors, such as ambient temperature and pathogen load, can significantly affect reproduction success. Bats are considered natural reservoirs for a wide variety of pathogenic agents, and have developed strong immune systems to cope. Nevertheless, very little is known about the influence of these pathogenic microorganisms on bat health as most infections are asymptomatic. In this study, we monitored presence of non-tuberculous mycobacteria (NTM) in female common noctule bats Nyctalus noctula during gestation. Eight NTM species, subspecies or complexes (Risk Group 1: Mycobacterium hiberniae and M. terrae complex. Risk Group 2: M. arupense, M. avium ssp. hominissuis, M. fortuitum, M. interjectum, M. peregrinum, M. septicum) were confirmed as part of the female gut microbiome during gestation, with representation changing during foetal development. Following hibernation, most females were infected, though infection load and severity were relatively low. Just prior to parturition, however, a high proportion of females were infected with a high, often pathogenic, NTM load. Females who gave birth to twins had a higher (though non-significant) proportion of positive samples after hibernation and before parturition. Negative correlations between two consecutive measurements suggest that female N. noctula can cope with NTM loading, even during energy-demanding pregnancies. Bat faeces appear to be a source of numerous NTM species and, as such, bats can be considered as vectors for NTM spread in the environment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10613 - Zoology

Projekt

<a href="/cs/project/GA21-12719S" target="_blank" >GA21-12719S: Mykobakterie u netopýrů a jejich role ve zdraví a nemoci</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Chiropterologica

ISSN

1508-1109

e-ISSN

1733-5329

Svazek periodika

25

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

11

Strana od-do

351-361

Kód UT WoS článku

001191883000013

EID výsledku v databázi Scopus

2-s2.0-85185343326