Electrochemical Analysis of Metallothionein in Chicken Exposed to Cadmium Ions
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F15%3A43907663" target="_blank" >RIV/62156489:43410/15:43907663 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/68407700:21730/15:00239417 RIV/00216305:26620/15:PU117629
Výsledek na webu
<a href="http://www.electrochemsci.org/papers/vol10/100503923.pdf" target="_blank" >http://www.electrochemsci.org/papers/vol10/100503923.pdf</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Electrochemical Analysis of Metallothionein in Chicken Exposed to Cadmium Ions
Popis výsledku v původním jazyce
Metallothionein as a protective protein has been studied in relationship to cancer diseases, toxicity of anticancer drugs and environmental pollution. Its electrochemical detection is based on Brdicka's reaction suitable for the protein detection. The original reaction was invented by Rudolf Brdicka in 1930s and adapted protocol of the reaction was utilized in this study. We focused on the effect of cadmium ions contained in CdTe quantum dots in comparison to cadmium ions in a standard solution appliedto chicken embryos. One day after application, chicken embryos were euthanized and liver, kidney, brain and muscle tissue were analyzed. The highest metallothionein levels were detected in the liver and kidney, which corresponded with cadmium accumulation determined by atomic absorption spectroscopy (68 mu g/g liver tissue and 125 mu g/g kidney tissue after application of quantum dots). The shape of electrochemical voltammograms was mathematically processed. In conclusion, metallothionei
Název v anglickém jazyce
Electrochemical Analysis of Metallothionein in Chicken Exposed to Cadmium Ions
Popis výsledku anglicky
Metallothionein as a protective protein has been studied in relationship to cancer diseases, toxicity of anticancer drugs and environmental pollution. Its electrochemical detection is based on Brdicka's reaction suitable for the protein detection. The original reaction was invented by Rudolf Brdicka in 1930s and adapted protocol of the reaction was utilized in this study. We focused on the effect of cadmium ions contained in CdTe quantum dots in comparison to cadmium ions in a standard solution appliedto chicken embryos. One day after application, chicken embryos were euthanized and liver, kidney, brain and muscle tissue were analyzed. The highest metallothionein levels were detected in the liver and kidney, which corresponded with cadmium accumulation determined by atomic absorption spectroscopy (68 mu g/g liver tissue and 125 mu g/g kidney tissue after application of quantum dots). The shape of electrochemical voltammograms was mathematically processed. In conclusion, metallothionei
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CG - Elektrochemie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/EE2.3.20.0148" target="_blank" >EE2.3.20.0148: Mezinárodní spolupráce v oblasti "in vivo" zobrazovacích technik</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
International Journal of Electrochemical Science
ISSN
1452-3981
e-ISSN
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Svazek periodika
10
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
CS - Srbsko a Černá Hora
Počet stran výsledku
12
Strana od-do
3923-3934
Kód UT WoS článku
000354782200020
EID výsledku v databázi Scopus
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