Introduction to long noncoding RNA

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43410%2F25%3A43926672" target="_blank" >RIV/62156489:43410/25:43926672 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/B978-0-443-21784-5.00011-3" target="_blank" >https://doi.org/10.1016/B978-0-443-21784-5.00011-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-443-21784-5.00011-3" target="_blank" >10.1016/B978-0-443-21784-5.00011-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Introduction to long noncoding RNA

Popis výsledku v původním jazyce

Research from several sources led to one of the most important findings in population genetics. They demonstrated how the size of the breeding population within a species affects natural selection&apos;s capacity to eliminate marginally harmful mutations. The greater the population size, the more adept natural selection is at spotting and removing marginally harmful mutations. The effective population size is much lower than the total population due to specific population dynamics factors. In fact, there is an inverse linear relationship between the size of the effective population and the degree of mutational harm required for natural selection to successfully remove a mutation from a population. Genetic drift alone will cause certain neutral and marginally harmful mutations to become fixed in the absence of selection pressure. It&apos;s crucial to understand that this relationship holds true for mutations that are only marginally helpful as well. Specifically, there is an inverse relationship between the effective population size and the level of benefit required for a mutation to be effectively chosen for by natural selection. Because of this, it is crucial to consider how a genetic modification impacts the organism&apos;s fitness and whether, given the size of the population, selection might influence this change in a positive or negative way. In the early and middle of the first decade of the 21st century, global transcriptomic analyses which aimed to better define the proteomeunveiled a novel surprise and posed a challenge to the conventional understanding of genetic information: the majority of the genomes of plants and animals are dynamically transcribed into longer RNAs with little to no potential to code for proteins. The majority of the transcriptome products produced by eukaryotic transcription lack the ability to code for proteins. The misclassification of noncoding RNAs as &quot;useless&quot; has largely contributed to the delay in our understanding of their functional activities. Despite not being able to convert into proteins, noncoding RNAs (ncRNAs) are nevertheless crucial for plant growth, development, and response to abiotic stress. Diverging in both biogenesis pathways and functional roles, noncoding. The unearthing of ncRNA has sparked a revolution in comprehending the intricacy and multiplicity of gene regulation within plants. Amidst the sundry ncRNA classes, one captivating and pivotal group has emerged: transposable element-derived noncoding RNAs(TE-derived ncRNAs).

Název v anglickém jazyce

Introduction to long noncoding RNA

Popis výsledku anglicky

Research from several sources led to one of the most important findings in population genetics. They demonstrated how the size of the breeding population within a species affects natural selection&apos;s capacity to eliminate marginally harmful mutations. The greater the population size, the more adept natural selection is at spotting and removing marginally harmful mutations. The effective population size is much lower than the total population due to specific population dynamics factors. In fact, there is an inverse linear relationship between the size of the effective population and the degree of mutational harm required for natural selection to successfully remove a mutation from a population. Genetic drift alone will cause certain neutral and marginally harmful mutations to become fixed in the absence of selection pressure. It&apos;s crucial to understand that this relationship holds true for mutations that are only marginally helpful as well. Specifically, there is an inverse relationship between the effective population size and the level of benefit required for a mutation to be effectively chosen for by natural selection. Because of this, it is crucial to consider how a genetic modification impacts the organism&apos;s fitness and whether, given the size of the population, selection might influence this change in a positive or negative way. In the early and middle of the first decade of the 21st century, global transcriptomic analyses which aimed to better define the proteomeunveiled a novel surprise and posed a challenge to the conventional understanding of genetic information: the majority of the genomes of plants and animals are dynamically transcribed into longer RNAs with little to no potential to code for proteins. The majority of the transcriptome products produced by eukaryotic transcription lack the ability to code for proteins. The misclassification of noncoding RNAs as &quot;useless&quot; has largely contributed to the delay in our understanding of their functional activities. Despite not being able to convert into proteins, noncoding RNAs (ncRNAs) are nevertheless crucial for plant growth, development, and response to abiotic stress. Diverging in both biogenesis pathways and functional roles, noncoding. The unearthing of ncRNA has sparked a revolution in comprehending the intricacy and multiplicity of gene regulation within plants. Amidst the sundry ncRNA classes, one captivating and pivotal group has emerged: transposable element-derived noncoding RNAs(TE-derived ncRNAs).

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

40101 - Agriculture

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Non-coding RNA in Plants: Modulation and Stress Responses

ISBN

978-0-443-21784-5

Počet stran výsledku

12

Strana od-do

1-12

Počet stran knihy

358

Název nakladatele

Elsevier Science Inc.

Místo vydání

New York

Kód UT WoS kapitoly

—