Stanovení imunoreaktivního kortizolu v moči psů a jeho validita při diagnostice hyperadrenokorticizmu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F00%3A00000263" target="_blank" >RIV/62157124:16170/00:00000263 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Immunoreactive cortisol measurement in canine urine and its validity in hyperadrenocorticosm diagnosis

Popis výsledku v původním jazyce

The aim of this study was to compare two methods of immunoreactive cortisol determination in urine and an assessment of the validity of urine cortisol/creatinine ratio (UCCR) in dogs. The UCCR was measured in three groups of dogs: (1) healthy dogs, (2) dogs with hyperadrenocorticism and (3) dogs suffering from other diseases presented with polyuria and polydipsia (PU/PD). All cortisol measurements in urine were performed using two methods: (1) fluorescence polarisation immunoassay (FPIA) with urine extrction and (2) radioimmunoassay (RIA) without urine extraction. Paired results of 30 cortisol measurements and 30 UCCR were compared using the Wilcoxon test. It was proved that the differences between the two methods (i.e., FPIA with the urine extractionand RIA without urine extraction) were highly statistically significant (p<0.01). While in the cortisol measurement using the FPIA with urine extraction the median of the UCCR amunted to 18.53 x 10-6, in the RIA without urine extraction i

Název v anglickém jazyce

Immunoreactive cortisol measurement in canine urine and its validity in hyperadrenocorticosm diagnosis

Popis výsledku anglicky

The aim of this study was to compare two methods of immunoreactive cortisol determination in urine and an assessment of the validity of urine cortisol/creatinine ratio (UCCR) in dogs. The UCCR was measured in three groups of dogs: (1) healthy dogs, (2) dogs with hyperadrenocorticism and (3) dogs suffering from other diseases presented with polyuria and polydipsia (PU/PD). All cortisol measurements in urine were performed using two methods: (1) fluorescence polarisation immunoassay (FPIA) with urine extrction and (2) radioimmunoassay (RIA) without urine extraction. Paired results of 30 cortisol measurements and 30 UCCR were compared using the Wilcoxon test. It was proved that the differences between the two methods (i.e., FPIA with the urine extractionand RIA without urine extraction) were highly statistically significant (p<0.01). While in the cortisol measurement using the FPIA with urine extraction the median of the UCCR amunted to 18.53 x 10-6, in the RIA without urine extraction i

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

217-223

Kód UT WoS článku

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EID výsledku v databázi Scopus

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