Immunoreactive Cortisol Measurement in Canine Urine and its Validity in Hyperadrenocorticism Diagnosis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F00%3A00000325" target="_blank" >RIV/62157124:16170/00:00000325 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Immunoreactive Cortisol Measurement in Canine Urine and its Validity in Hyperadrenocorticism Diagnosis

Popis výsledku v původním jazyce

The aim of this study was to compare two methods of immunoreactive cortisol determination in urine and an assesssment of the validity of urine cortisol/creatinine ratio (UCCR) in dogs. The UCCR was measured in three groups of dogs: (1) healthy dogs, (2)dogs with hyperadrenocorticism and (3) dogs suffering from other diseases presented with polyuria and polydipsia (PU/PD). All cortisol measurements in urine were performed using two methods: (1) fluorescence polarisation immunoassay (FPIA) with urine extraction and (2) radioimmunoassay without urine extraction. Paired results of 30 cortisol measurement and 30 UCCR were compared using the Wilcoxon test. It was proved that the difference between the two methods (i. e., FPIA with urine extraction and RIA without urine extraction) were highly statistically significant (p < 0,01). While in the cortisol measurement using the FPIA with urine extraction the median of the UCCR amounted to 18, 53 x 10-6, in the RIA without extraction it was 37,83

Název v anglickém jazyce

Immunoreactive Cortisol Measurement in Canine Urine and its Validity in Hyperadrenocorticism Diagnosis

Popis výsledku anglicky

The aim of this study was to compare two methods of immunoreactive cortisol determination in urine and an assesssment of the validity of urine cortisol/creatinine ratio (UCCR) in dogs. The UCCR was measured in three groups of dogs: (1) healthy dogs, (2)dogs with hyperadrenocorticism and (3) dogs suffering from other diseases presented with polyuria and polydipsia (PU/PD). All cortisol measurements in urine were performed using two methods: (1) fluorescence polarisation immunoassay (FPIA) with urine extraction and (2) radioimmunoassay without urine extraction. Paired results of 30 cortisol measurement and 30 UCCR were compared using the Wilcoxon test. It was proved that the difference between the two methods (i. e., FPIA with urine extraction and RIA without urine extraction) were highly statistically significant (p < 0,01). While in the cortisol measurement using the FPIA with urine extraction the median of the UCCR amounted to 18, 53 x 10-6, in the RIA without extraction it was 37,83

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2000

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Veterinaria (Brno)

ISSN

0001-7213

e-ISSN

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Svazek periodika

69

Číslo periodika v rámci svazku

41

Stát vydavatele periodika

XX - osoby bez státní příslušnosti

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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